ENSGALG00000010589


Gallus gallus

Features
Gene ID: ENSGALG00000010589
  
Biological name :FLRT2
  
Synonyms : fibronectin leucine rich transmembrane protein 2 / FLRT2
  
Possible biological names infered from orthology : Leucine-rich repeat transmembrane protein FLRT2 / O43155 / Q8BLU0
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 42229429
Gene end: 42231417
  
Corresponding Affymetrix probe sets: Gga.11930.1.S1_at (Chicken Array)   Gga.11930.1.S1_s_at (Chicken Array)   Gga.18401.1.S1_at (Chicken Array)   GgaAffx.23256.1.A1_at (Chicken Array)   GgaAffx.23256.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000017210
NCBI entrez gene - 428901     See in Manteia.
RefSeq - XM_003641305
RefSeq - XM_004941848
swissprot - E1C6W5
Ensembl - ENSGALG00000010589
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 flrt2ENSDARG00000079355Danio rerio
 flrt2ENSDARG00000097299Danio rerio
 FLRT2ENSG00000185070Homo sapiens
 Flrt2ENSMUSG00000047414Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FLRT3 / F1NUK7 / Leucine-rich repeat transmembrane protein FLRT3 / Q8BGT1* / Q9NZU0* / fibronectin leucine rich transmembrane protein 3*ENSGALG0000000871645
Nepn* / Q9CQ76* / Nephrocan *ENSGALG0000001490016
OMG / oligodendrocyte myelin glycoprotein / P23515*ENSGALG0000000559413
LRG1 / leucine rich alpha-2-glycoprotein 1 / P02750*ENSGALG0000002758711


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003007 heart morphogenesis IEA
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 biological_processGO:0050919 negative chemotaxis IEA
 biological_processGO:0051965 positive regulation of synapse assembly IEA
 biological_processGO:0061343 cell adhesion involved in heart morphogenesis IEA
 biological_processGO:0071711 basement membrane organization IEA
 biological_processGO:2001222 regulation of neuron migration IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0005104 fibroblast growth factor receptor binding IEA
 molecular_functionGO:0045499 chemorepellent activity IEA


Pathways (from Reactome)
Pathway description
Downstream signaling of activated FGFR1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000017068 KL / klotho / O35082* / Q9UEF7* / Klotho Klotho peptide*  / complex / reaction
 ENSGALG00000027791 FGF23 / fibroblast growth factor 23 / Q9EPC2* / Q9GZV9*  / complex / reaction
 ENSGALG00000039786 FGFR1 / fibroblast growth factor receptor 1 precursor / P11362* / P16092* / fibroblast growth factor receptor 1*  / reaction / complex






 

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