ENSDARG00000079355


Danio rerio

Features
Gene ID: ENSDARG00000079355
  
Biological name :flrt2
  
Synonyms : fibronectin leucine rich transmembrane protein 2 / flrt2
  
Possible biological names infered from orthology : Leucine-rich repeat transmembrane protein FLRT2 / O43155 / Q8BLU0
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 11098239
Gene end: 11178022
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000126632
NCBI entrez gene - 571972     See in Manteia.
swissprot - A5WWE9
ZFIN ID - ZDB-GENE-070705-267
Ensembl - ENSDARG00000079355
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FLRT2ENSGALG00000010589Gallus gallus
 FLRT2ENSG00000185070Homo sapiens
 Flrt2ENSMUSG00000047414Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
flrt2 / fibronectin leucine rich transmembrane protein 2 / O43155* / Q8BLU0* / Leucine-rich repeat transmembrane protein FLRT2 *ENSDARG0000009729967
flrt3 / fibronectin leucine rich transmembrane 3 / Q8BGT1* / Q9NZU0* / fibronectin leucine rich transmembrane protein 3* / Leucine-rich repeat transmembrane protein FLRT3 *ENSDARG0000007689543
flrt1b / fibronectin leucine rich transmembrane protein 1b / FLRT1* / Q6RKD8* / Q9NZU1* / fibronectin leucine rich transmembrane protein 1* / Leucine-rich repeat transmembrane protein FLRT1 *ENSDARG0000007559737
si:dkey-90m5.4 / LRG1* / P02750* / leucine rich alpha-2-glycoprotein 1*ENSDARG0000002938812
si:ch211-191d15.2 / Nepn* / Q9CQ76* / Nephrocan *ENSDARG0000009283411
omgb / oligodendrocyte myelin glycoprotein b / OMG* / P23515* / oligodendrocyte myelin glycoprotein*ENSDARG0000008944411
omga / oligodendrocyte myelin glycoprotein a / OMG* / P23515* / oligodendrocyte myelin glycoprotein*ENSDARG000000865738


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA


Pathways (from Reactome)
Pathway description
Downstream signaling of activated FGFR1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000011027 fgfr1a / Q90Z00 / fibroblast growth factor receptor 1a / FGFR1* / P11362* / P16092* / fibroblast growth factor receptor 1*  / reaction / complex
 ENSDARG00000030932 fgf10a / fibroblast growth factor 10a / FGF10* / O35565* / O15520* / fibroblast growth factor 10*  / complex / reaction
 ENSDARG00000011190 fgfr1b / fibroblast growth factor receptor 1b / FGFR1* / P16092* / P11362* / fibroblast growth factor receptor 1*  / reaction / complex
 ENSDARG00000076510 fgf22 / fibroblast growth factor 22 / Q9ESS2* / Q9HCT0*  / complex / reaction
 ENSDARG00000079862 kl / klotho / O35082* / Q9UEF7* / Klotho Klotho peptide*  / reaction / complex
 ENSDARG00000100475 fgf10b / fibroblast growth factor 10b / FGF10* / O15520* / fibroblast growth factor 10*  / complex / reaction
 ENSDARG00000101540 fgf3 / P48802 / fibroblast growth factor 3 / P11487*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr