ENSGALG00000010692


Gallus gallus

Features
Gene ID: ENSGALG00000010692
  
Biological name :LRP8
  
Synonyms : low-density lipoprotein receptor-related protein 8 precursor / LRP8
  
Possible biological names infered from orthology : LDL receptor related protein 8 / Low-density lipoprotein receptor-related protein 8 / Q14114 / Q924X6
  
Species: Gallus gallus
  
Chr. number: 8
Strand: -1
Band:
Gene start: 24742974
Gene end: 24890035
  
Corresponding Affymetrix probe sets: Gga.3461.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000017370
NCBI entrez gene - 396102     See in Manteia.
RefSeq - NM_205186
RefSeq Peptide - NP_990517
swissprot - F1NS31
Ensembl - ENSGALG00000010692
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrp8ENSDARG00000070074Danio rerio
 LRP8ENSG00000157193Homo sapiens
 Lrp8ENSMUSG00000028613Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
VLDLR / P98165 / Very low-density lipoprotein receptor / P98155* / P98156*ENSGALG0000001016650
LRP2 / LDL receptor related protein 2 / A2ARV4* / P98164* / low density lipoprotein receptor-related protein 2*ENSGALG0000001085835
LRP1B / LDL receptor related protein 1B / Q9NZR2*ENSGALG0000001240735
LRP4 / LDL receptor related protein 4 / O75096* / Q8VI56* / Low-density lipoprotein receptor-related protein 4 *ENSGALG0000003218133
Gm19410*ENSGALG0000002317223
LRP6 / LDL receptor related protein 6 / O75581*ENSGALG0000003150317
LRP5 / low-density lipoprotein receptor-related protein 5 precursor / O75197* / Q91VN0* / LDL receptor related protein 5* / Low-density lipoprotein receptor-related protein 5 *ENSGALG0000002953316


Protein motifs (from Interpro)
Interpro ID Name
 IPR000033  LDLR class B repeat
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site
 IPR023415  Low-density lipoprotein (LDL) receptor class A, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 cellular_componentGO:0005901 caveola IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0030229 very-low-density lipoprotein particle receptor activity IEA


Pathways (from Reactome)
Pathway description
Platelet sensitization by LDL


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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