ENSGALG00000010850


Gallus gallus

Features
Gene ID: ENSGALG00000010850
  
Biological name :C8A
  
Synonyms : C8A / complement C8 alpha chain
  
Possible biological names infered from orthology : Complement component C8 alpha chain / P07357 / Q8K182
  
Species: Gallus gallus
  
Chr. number: 8
Strand: 1
Band:
Gene start: 25885358
Gene end: 25901235
  
Corresponding Affymetrix probe sets: GgaAffx.6854.1.S1_s_at (Chicken Array)   GgaAffx.6854.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000017612
NCBI entrez gene - 429111     See in Manteia.
RefSeq - XM_015291182
RefSeq - XM_426667
swissprot - F1NJU5
Ensembl - ENSGALG00000010850
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 c8aENSDARG00000039516Danio rerio
 C8AENSG00000157131Homo sapiens
 C8aENSMUSG00000035031Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
C6 / complement C6 / P13671* / complement component 6*ENSGALG0000001484031
C8B / Gallus gallus complement C8 beta chain (C8B), mRNA. / P07358* / Q8BH35* / complement C8 beta chain* / Complement component C8 beta chain *ENSGALG0000001085328
C7 / Gallus gallus complement C7 (C7), mRNA. / P10643* / complement C7* / complement component 7*ENSGALG0000001483525


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001862  Membrane attack complex component/perforin/complement C9
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR013032  EGF-like, conserved site
 IPR020863  Membrane attack complex component/perforin domain, conserved site
 IPR020864  Membrane attack complex component/perforin (MACPF) domain
 IPR023415  Low-density lipoprotein (LDL) receptor class A, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response IEA
 biological_processGO:0006956 complement activation IEA
 cellular_componentGO:0005579 membrane attack complex IEA


Pathways (from Reactome)
Pathway description
Terminal pathway of complement
Formation of membrane attack complex (MAC)
Regulation of complement cascades
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001565 C5 / complement C5 / Hc* / P01031* / P06684* / hemolytic complement*  / reaction / complex
 ENSGALG00000014840 C6 / complement C6 / P13671* / complement component 6*  / reaction / complex
 ENSGALG00000043051 CLU / clusterin precursor / P10909* / Q06890* / clusterin* / Clusterin Clusterin beta chain Clusterin alpha chain*  / reaction / complex
 ENSGALG00000010853 C8B / Gallus gallus complement C8 beta chain (C8B), mRNA. / P07358* / Q8BH35* / complement C8 beta chain* / Complement component C8 beta chain *  / complex






 

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