ENSGALG00000014840


Gallus gallus

Features
Gene ID: ENSGALG00000014840
  
Biological name :C6
  
Synonyms : C6 / complement C6
  
Possible biological names infered from orthology : complement component 6 / P13671
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 12966009
Gene end: 12990144
  
Corresponding Affymetrix probe sets: GgaAffx.9434.1.S1_s_at (Chicken Array)   GgaAffx.9434.3.S1_at (Chicken Array)   GgaAffx.9434.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000023910
NCBI entrez gene - 431585     See in Manteia.
RefSeq - XM_015277352
RefSeq - NM_001144849
RefSeq - XM_015277349
RefSeq - XM_015277351
RefSeq Peptide - NP_001138321
swissprot - B8ZX71
Ensembl - ENSGALG00000014840
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 c6ENSDARG00000057113Danio rerio
 c6ENSDARG00000093052Danio rerio
 C6ENSG00000039537Homo sapiens
 C6ENSMUSG00000022181Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
C7 / Gallus gallus complement C7 (C7), mRNA. / P10643* / complement C7* / complement component 7*ENSGALG0000001483527
C8A / complement C8 alpha chain / P07357* / Q8K182* / Complement component C8 alpha chain *ENSGALG0000001085020
C8B / Gallus gallus complement C8 beta chain (C8B), mRNA. / P07358* / Q8BH35* / complement C8 beta chain* / Complement component C8 beta chain *ENSGALG0000001085319


Protein motifs (from Interpro)
Interpro ID Name
 IPR000436  Sushi/SCR/CCP domain
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001862  Membrane attack complex component/perforin/complement C9
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR003884  Factor I / membrane attack complex
 IPR020863  Membrane attack complex component/perforin domain, conserved site
 IPR020864  Membrane attack complex component/perforin (MACPF) domain
 IPR023415  Low-density lipoprotein (LDL) receptor class A, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001970 positive regulation of activation of membrane attack complex IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0006956 complement activation IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0045917 positive regulation of complement activation IEA
 cellular_componentGO:0005579 membrane attack complex IEA


Pathways (from Reactome)
Pathway description
Terminal pathway of complement
Formation of membrane attack complex (MAC)
Regulation of complement cascades
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001565 C5 / complement C5 / Hc* / P01031* / P06684* / hemolytic complement*  / complex / reaction
 ENSGALG00000010853 C8B / Gallus gallus complement C8 beta chain (C8B), mRNA. / P07358* / Q8BH35* / complement C8 beta chain* / Complement component C8 beta chain *  / complex / reaction
 ENSGALG00000043051 CLU / clusterin precursor / P10909* / Q06890* / clusterin* / Clusterin Clusterin beta chain Clusterin alpha chain*  / reaction / complex
 ENSGALG00000010850 C8A / complement C8 alpha chain / P07357* / Q8K182* / Complement component C8 alpha chain *  / reaction / complex






 

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