ENSGALG00000010853


Gallus gallus

Features
Gene ID: ENSGALG00000010853
  
Biological name :C8B
  
Synonyms : C8B / Gallus gallus complement C8 beta chain (C8B), mRNA.
  
Possible biological names infered from orthology : complement C8 beta chain / Complement component C8 beta chain / P07358 / Q8BH35
  
Species: Gallus gallus
  
Chr. number: 8
Strand: -1
Band:
Gene start: 25905426
Gene end: 25921408
  
Corresponding Affymetrix probe sets: Gga.10243.1.S1_at (Chicken Array)   Gga.9515.1.A1_at (Chicken Array)   Gga.9515.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000017617
NCBI entrez gene - 424669     See in Manteia.
RefSeq - NM_001321543
RefSeq - XM_422502
RefSeq Peptide - NP_001308472
swissprot - E1C7C1
Ensembl - ENSGALG00000010853
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 c8bENSDARG00000039517Danio rerio
 C8BENSG00000021852Homo sapiens
 C8bENSMUSG00000029656Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
C6 / complement C6 / P13671* / complement component 6*ENSGALG0000001484031
C8A / complement C8 alpha chain / P07357* / Q8K182* / Complement component C8 alpha chain *ENSGALG0000001085029
C7 / Gallus gallus complement C7 (C7), mRNA. / P10643* / complement C7* / complement component 7*ENSGALG0000001483525


Protein motifs (from Interpro)
Interpro ID Name
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001862  Membrane attack complex component/perforin/complement C9
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR020863  Membrane attack complex component/perforin domain, conserved site
 IPR020864  Membrane attack complex component/perforin (MACPF) domain
 IPR023415  Low-density lipoprotein (LDL) receptor class A, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response IEA
 biological_processGO:0006956 complement activation IEA
 cellular_componentGO:0005579 membrane attack complex IEA


Pathways (from Reactome)
Pathway description
Terminal pathway of complement
Formation of membrane attack complex (MAC)
Regulation of complement cascades
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001565 C5 / complement C5 / Hc* / P01031* / P06684* / hemolytic complement*  / reaction / complex
 ENSGALG00000014840 C6 / complement C6 / P13671* / complement component 6*  / complex / reaction
 ENSGALG00000043051 CLU / clusterin precursor / P10909* / Q06890* / clusterin* / Clusterin Clusterin beta chain Clusterin alpha chain*  / reaction / complex
 ENSGALG00000010850 C8A / complement C8 alpha chain / P07357* / Q8K182* / Complement component C8 alpha chain *  / complex






 

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