ENSGALG00000011744


Gallus gallus

Features
Gene ID: ENSGALG00000011744
  
Biological name :KALRN
  
Synonyms : kalirin RhoGEF kinase / KALRN
  
Possible biological names infered from orthology : A2CG49 / Kalirin / O60229
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 27566419
Gene end: 28008798
  
Corresponding Affymetrix probe sets: Gga.19549.1.S1_at (Chicken Array)   Gga.9576.1.S1_s_at (Chicken Array)   GgaAffx.23641.1.S1_s_at (Chicken Array)   GgaAffx.23641.3.S1_s_at (Chicken Array)   GgaAffx.7473.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047990
Ensembl peptide - ENSGALP00000055501
Ensembl peptide - ENSGALP00000019155
NCBI entrez gene - 424253     See in Manteia.
RefSeq - XM_015289987
RefSeq - XM_015289982
RefSeq - XM_015289983
RefSeq - XM_015289984
RefSeq - XM_015289974
RefSeq - XM_015289976
RefSeq - XM_015289977
RefSeq - XM_015289978
RefSeq - XM_015289979
RefSeq - XM_015289980
RefSeq - XM_015289981
swissprot - A0A1D5PRH4
swissprot - F1NPK0
swissprot - A0A1D5P5L9
Ensembl - ENSGALG00000011744
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FP015810.1ENSDARG00000112749Danio rerio
 kalrnaENSDARG00000104119Danio rerio
 kalrnbENSDARG00000063538Danio rerio
 KALRNENSG00000160145Homo sapiens
 KalrnENSMUSG00000061751Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TRIO / trio Rho guanine nucleotide exchange factor / O75962* / Q0KL02* / Triple functional domain protein *ENSGALG0000003149566
MCF2L / MCF.2 cell line derived transforming sequence like / O15068*ENSGALG0000001683411
MCF2L2 / MCF.2 cell line derived transforming sequence-like 2 / Q86YR7*ENSGALG0000000874410
MCF2 / MCF.2 cell line derived transforming sequence / P10911*ENSGALG0000000656210
PLEKHG1 / pleckstrin homology and RhoGEF domain containing G1 / Q9ULL1*ENSGALG000000123954
A1L390* / Q4VAC9* / PLEKHG3* / pleckstrin homology and RhoGEF domain containing G3* / Pleckstrin homology domain-containing family G member 3 *ENSGALG000000374093
A1L390* / Q4VAC9* / PLEKHG3* / pleckstrin homology and RhoGEF domain containing G3* / Pleckstrin homology domain-containing family G member 3 *ENSGALG000000361993


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR000719  Protein kinase domain
 IPR001251  CRAL-TRIO lipid binding domain
 IPR001452  SH3 domain
 IPR001849  Pleckstrin homology domain
 IPR002017  Spectrin repeat
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011993  PH-like domain superfamily
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR017441  Protein kinase, ATP binding site
 IPR018159  Spectrin/alpha-actinin
 IPR028569  Kalirin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
EPHB-mediated forward signaling
G alpha (q) signalling events
G alpha (12/13) signalling events
MAPK6/MAPK4 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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