ENSGALG00000012932


Gallus gallus

Features
Gene ID: ENSGALG00000012932
  
Biological name :FGD4
  
Synonyms : FGD4 / FYVE, RhoGEF and PH domain containing 4
  
Possible biological names infered from orthology : FYVE, RhoGEF and PH domain-containing protein 4 / Q91ZT5 / Q96M96
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 59021804
Gene end: 59039816
  
Corresponding Affymetrix probe sets: GgaAffx.8182.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000021062
Ensembl peptide - ENSGALP00000047298
NCBI entrez gene - 107049013     See in Manteia.
RefSeq - XM_015287255
swissprot - A0A1D5P3P3
swissprot - E1C246
Ensembl - ENSGALG00000012932
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fgd4aENSDARG00000101471Danio rerio
 fgd4bENSDARG00000060248Danio rerio
 FGD4ENSG00000139132Homo sapiens
 Fgd4ENSMUSG00000022788Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FGD3 / FYVE, RhoGEF and PH domain containing 3 / Q5JSP0*ENSGALG0000000523748
FGD6 / FYVE, RhoGEF and PH domain containing 6 / Q69ZL1* / Q6ZV73* / FYVE, RhoGEF and PH domain-containing protein 6 *ENSGALG0000001134229
FGD5 / FYVE, RhoGEF and PH domain containing 5 / Q6ZNL6*ENSGALG0000000854625
PLEKHF1 / pleckstrin homology and FYVE domain containing 1 / Q3TB82* / Q96S99* / Pleckstrin homology domain-containing family F member 1 *ENSGALG0000000447410
PLEKHF2 / pleckstrin homology domain-containing family F member 2 / Q91WB4* / Q9H8W4* / pleckstrin homology and FYVE domain containing 2*ENSGALG000000402489


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR000306  FYVE zinc finger
 IPR000315  B-box-type zinc finger
 IPR001849  Pleckstrin homology domain
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR011993  PH-like domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017455  Zinc finger, FYVE-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030032 lamellipodium assembly IEA
 biological_processGO:0030035 microspike assembly IEA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030175 filopodium IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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