ENSDARG00000101471


Danio rerio

Features
Gene ID: ENSDARG00000101471
  
Biological name :fgd4a
  
Synonyms : fgd4a / FYVE, RhoGEF and PH domain containing 4a
  
Possible biological names infered from orthology : FGD4 / FYVE, RhoGEF and PH domain containing 4 / FYVE, RhoGEF and PH domain-containing protein 4 / Q91ZT5 / Q96M96
  
Species: Danio rerio
  
Chr. number: 18
Strand: 1
Band:
Gene start: 12147971
Gene end: 12229524
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000135370
Ensembl peptide - ENSDARP00000138561
NCBI entrez gene - 556216     See in Manteia.
RefSeq - NM_001177933
RefSeq Peptide - NP_001171404
swissprot - F1QAA5
swissprot - A0A0J9YJA6
ZFIN ID - ZDB-GENE-050420-347
Ensembl - ENSDARG00000101471
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FGD4ENSGALG00000012932Gallus gallus
 FGD4ENSG00000139132Homo sapiens
 Fgd4ENSMUSG00000022788Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fgd4b / FYVE, RhoGEF and PH domain containing 4b / FGD4* / Q96M96* / FYVE, RhoGEF and PH domain containing 4*ENSDARG0000006024858
fgd1 / FYVE, RhoGEF and PH domain containing 1 / P52734* / P98174* / FYVE, RhoGEF and PH domain-containing protein 1 *ENSDARG0000010040244
CABZ01079663.1 / FGD3* / Q5JSP0* / FYVE, RhoGEF and PH domain containing 3*ENSDARG0000009965025
fgd6 / FYVE, RhoGEF and PH domain containing 6 / Q69ZL1* / Q6ZV73* / FYVE, RhoGEF and PH domain-containing protein 6 *ENSDARG0000004552825
fgd5a / FYVE, RhoGEF and PH domain containing 5a / FGD5* / Q6ZNL6* / FYVE, RhoGEF and PH domain containing 5*ENSDARG0000008880120
fgd5b / FYVE, RhoGEF and PH domain containing 5b / FGD5* / Q6ZNL6* / FYVE, RhoGEF and PH domain containing 5*ENSDARG0000008962214
Q7ZUV1 / plekhf2 / pleckstrin homology domain containing, family F (with FYVE domain) member 2 / Q91WB4* / Q9H8W4* / pleckstrin homology and FYVE domain containing 2* / Pleckstrin homology ...ENSDARG000000211419
plekhf1 / pleckstrin homology domain containing, family F (with FYVE domain) member 1 / Q3TB82* / Q96S99* / pleckstrin homology and FYVE domain containing 1* / Pleckstrin homology domain-co...ENSDARG000001024358


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR000306  FYVE zinc finger
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017455  Zinc finger, FYVE-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr