ENSGALG00000013022


Gallus gallus

Features
Gene ID: ENSGALG00000013022
  
Biological name :CACNA1C
  
Synonyms : CACNA1C / calcium voltage-gated channel subunit alpha1 C
  
Possible biological names infered from orthology : Q01815 / Q13936 / Voltage-dependent L-type calcium channel subunit alpha-1C
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 61471636
Gene end: 61671542
  
Corresponding Affymetrix probe sets: Gga.525.1.S1_at (Chicken Array)   GgaAffx.8253.1.S1_at (Chicken Array)   GgaAffx.8254.1.S1_at (Chicken Array)   GgaAffx.8255.1.S1_at (Chicken Array)   GgaAffx.8256.1.S1_at (Chicken Array)   GgaAffx.8259.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045304
Ensembl peptide - ENSGALP00000021230
NCBI entrez gene - 395891     See in Manteia.
RefSeq - XM_015286657
RefSeq - XM_015286643
RefSeq - XM_015286652
RefSeq - XM_015286441
RefSeq - XM_015286450
RefSeq - XM_015286459
RefSeq - XM_015286464
RefSeq - XM_015286473
RefSeq - XM_015286478
RefSeq - XM_015286485
RefSeq - XM_015286492
RefSeq - XM_015286498
RefSeq - XM_015286507
RefSeq - XM_015286510
RefSeq - XM_015286516
RefSeq - XM_015286520
RefSeq - XM_015286524
RefSeq - XM_015286529
RefSeq - XM_015286536
RefSeq - XM_015286547
RefSeq - XM_015286558
RefSeq - XM_015286569
RefSeq - XM_015286578
RefSeq - XM_015286581
RefSeq - XM_015286584
RefSeq - XM_015286591
RefSeq - XM_015286598
RefSeq - XM_015286607
RefSeq - XM_015286615
RefSeq - XM_015286620
RefSeq - XM_015286628
RefSeq - XM_015286633
swissprot - F1NJP7
swissprot - A0A1D5NY49
Ensembl - ENSGALG00000013022
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cacna1cENSDARG00000008398Danio rerio
 Q13936ENSG00000151067Homo sapiens
 Q01815ENSMUSG00000051331Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O73700 / CACNA1D / Voltage-dependent L-type calcium channel subunit alpha-1D / Q01668* / Q99246* / calcium voltage-gated channel subunit alpha1 D*ENSGALG0000000533267
CACNA1S / voltage-dependent L-type calcium channel subunit alpha-1S isoform 1 / Q13698* / calcium voltage-gated channel subunit alpha1 S*ENSGALG0000003774457
CACNA1B / voltage-dependent N-type calcium channel subunit alpha-1B / O55017* / Q00975* / calcium voltage-gated channel subunit alpha1 B*ENSGALG0000000845640
CACNA1E / calcium voltage-gated channel subunit alpha1 E / Q15878*ENSGALG0000000383337
NALCN / sodium leak channel, non-selective / Q8IZF0*ENSGALG0000001686818


Protein motifs (from Interpro)
Interpro ID Name
 IPR002077  Voltage-dependent calcium channel, alpha-1 subunit
 IPR005446  Voltage-dependent calcium channel, L-type, alpha-1 subunit
 IPR005451  Voltage-dependent calcium channel, L-type, alpha-1C subunit
 IPR005821  Ion transport domain
 IPR014873  Voltage-dependent calcium channel, alpha-1 subunit, IQ domain
 IPR027359  Voltage-dependent channel domain superfamily
 IPR031649  Voltage-dependent L-type calcium channel, IQ-associated domain
 IPR031688  Voltage-gated calcium channel subunit alpha, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002520 immune system development IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0035115 embryonic forelimb morphogenesis IEA
 biological_processGO:0043010 camera-type eye development IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0061337 cardiac conduction IEA
 biological_processGO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:0086002 cardiac muscle cell action potential involved in contraction IEA
 biological_processGO:0086010 membrane depolarization during action potential IBA
 biological_processGO:0086012 membrane depolarization during cardiac muscle cell action potential IEA
 biological_processGO:0086045 membrane depolarization during AV node cell action potential IEA
 biological_processGO:0086091 regulation of heart rate by cardiac conduction IEA
 biological_processGO:0098911 regulation of ventricular cardiac muscle cell action potential IEA
 biological_processGO:0098912 membrane depolarization during atrial cardiac muscle cell action potential IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005891 voltage-gated calcium channel complex IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:1990454 L-type voltage-gated calcium channel complex IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005245 voltage-gated calcium channel activity IEA
 molecular_functionGO:0005262 calcium channel activity IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0008331 high voltage-gated calcium channel activity IEA
 molecular_functionGO:0051393 alpha-actinin binding IEA
 molecular_functionGO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential IEA
 molecular_functionGO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential IEA


Pathways (from Reactome)
Pathway description
Regulation of insulin secretion
Phase 0 - rapid depolarisation
Phase 2 - plateau phase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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