ENSGALG00000013039


Gallus gallus

Features
Gene ID: ENSGALG00000013039
  
Biological name :BID
  
Synonyms : BH3 interacting domain death agonist / BID
  
Possible biological names infered from orthology : BH3-interacting domain death agonist BH3-interacting domain death agonist p15 BH3-interacting domain death agonist p13 BH3-interacting domain death agonist p11 / P55957 / P70444
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 61913394
Gene end: 61932331
  
Corresponding Affymetrix probe sets: Gga.1234.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000021253
Ensembl peptide - ENSGALP00000056741
Ensembl peptide - ENSGALP00000048995
NCBI entrez gene - 395236     See in Manteia.
RefSeq - NM_204552
RefSeq - XM_015284410
RefSeq - XM_015284413
RefSeq Peptide - NP_989883
swissprot - A0A1D5P8E8
swissprot - A0A140T8G9
Ensembl - ENSGALG00000013039
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BIDENSG00000015475Homo sapiens
 BidENSMUSG00000004446Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR010479  BH3-interacting domain death agonist


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001836 release of cytochrome c from mitochondria IEA
 biological_processGO:0006626 protein targeting to mitochondrion IEA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0008637 apoptotic mitochondrial changes IEA
 biological_processGO:0010918 positive regulation of mitochondrial membrane potential IEA
 biological_processGO:0032459 regulation of protein oligomerization IEA
 biological_processGO:0032461 positive regulation of protein oligomerization IEA
 biological_processGO:0032464 positive regulation of protein homooligomerization IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0042775 mitochondrial ATP synthesis coupled electron transport IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0090150 establishment of protein localization to membrane IEA
 biological_processGO:0090200 positive regulation of release of cytochrome c from mitochondria IEA
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IEA
 biological_processGO:0097284 hepatocyte apoptotic process IEA
 biological_processGO:0097345 mitochondrial outer membrane permeabilization IEA
 biological_processGO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process IEA
 biological_processGO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage IEA
 biological_processGO:2000045 regulation of G1/S transition of mitotic cell cycle IEA
 biological_processGO:2000271 positive regulation of fibroblast apoptotic process IEA
 biological_processGO:2001235 positive regulation of apoptotic signaling pathway IEA
 biological_processGO:2001238 positive regulation of extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0032592 integral component of mitochondrial membrane IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Activation and oligomerization of BAK protein
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
Activation, myristolyation of BID and translocation to mitochondria


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000857 NMT1 / N-myristoyltransferase 1 / O70310* / P30419* / Glycylpeptide N-tetradecanoyltransferase 1 *  / reaction
 ENSGALG00000006211 Q07816 / BCL2L1 / Bcl-2-like protein 1 / Q64373* / Q07817* / BCL2 like 1* / Mus musculus BCL2-like 1 (Bcl2l1), transcript variant 5, mRNA.*  / complex / reaction
 ENSGALG00000012885 BCL2 / Q00709 / Apoptosis regulator Bcl-2 / P10415* / P10417* / BCL2, apoptosis regulator*  / complex / reaction
 ENSGALG00000031493 BAK1 / BCL2 antagonist/killer 1 / O08734* / Q16611* / Bcl-2 homologous antagonist/killer *  / complex / reaction






 

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