ENSGALG00000013468


Gallus gallus

Features
Gene ID: ENSGALG00000013468
  
Biological name :TLR3
  
Synonyms : TLR3 / toll-like receptor 3 precursor
  
Possible biological names infered from orthology : Mus musculus toll-like receptor 3 (Tlr3), transcript variant 3, mRNA. / O15455 / Q99MB1 / toll like receptor 3
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 61707202
Gene end: 61720669
  
Corresponding Affymetrix probe sets: Gga.19919.1.A1_at (Chicken Array)   Gga.19919.1.S1_at (Chicken Array)   GgaAffx.8585.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000021914
NCBI entrez gene - 422720     See in Manteia.
RefSeq - NM_001011691
RefSeq - XM_015285432
RefSeq Peptide - NP_001011691
swissprot - F1NG27
Ensembl - ENSGALG00000013468
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tlr3ENSDARG00000016065Danio rerio
 TLR3ENSG00000164342Homo sapiens
 Tlr3ENSMUSG00000031639Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TLR7 / toll-like receptor 7 / P58681* / Q9NYK1*ENSGALG0000001659020
TLR21 / Toll-like receptor 21 precursor / Tlr13* / Q6R5N8* / Toll-like receptor 13 *ENSGALG0000003306819
TLR4 / toll-like receptor 4 precursor / O00206* / Q9QUK6* / toll like receptor 4*ENSGALG0000000700117
TLR5 / toll-like receptor 5 precursor / O60602* / toll like receptor 5*ENSGALG0000000939217
TLR2B / toll-like receptor 2 type-2 precursor / TLR2* / O60603* / toll like receptor 2*ENSGALG0000003472216
TLR1A / toll-like receptor1 precursor / TLR1* / TLR6* / TLR10* / Q15399* / Q9EPQ1* / Q9BXR5* / Q9Y2C9* / toll like receptor 1* / toll like receptor 6* / toll like receptor 10*ENSGALG0000001748515
TLR15 / Gallus gallus toll-like receptor 15 (TLR15), mRNA.ENSGALG0000000816613
TLR1B / toll-like receptor 6 / TLR1* / TLR6* / TLR10* / Q15399* / Q9Y2C9* / Q9BXR5* / Q9EPQ1* / toll like receptor 1* / toll like receptor 10*ENSGALG0000002709312
CD180 / CD180 molecule / Q62192* / Q99467* / CD180 antigen *ENSGALG0000002341111


Protein motifs (from Interpro)
Interpro ID Name
 IPR000157  Toll/interleukin-1 receptor homology (TIR) domain
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR027173  Toll-like receptor 3
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001819 positive regulation of cytokine production IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002730 regulation of dendritic cell cytokine production IEA
 biological_processGO:0002756 MyD88-independent toll-like receptor signaling pathway IEA
 biological_processGO:0006952 defense response IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007252 I-kappaB phosphorylation IEA
 biological_processGO:0009615 response to virus IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0032481 positive regulation of type I interferon production IEA
 biological_processGO:0032722 positive regulation of chemokine production IEA
 biological_processGO:0032728 positive regulation of interferon-beta production IEA
 biological_processGO:0032735 positive regulation of interleukin-12 production IEA
 biological_processGO:0032755 positive regulation of interleukin-6 production IEA
 biological_processGO:0032757 positive regulation of interleukin-8 production IEA
 biological_processGO:0032760 positive regulation of tumor necrosis factor production IEA
 biological_processGO:0034123 positive regulation of toll-like receptor signaling pathway IEA
 biological_processGO:0034138 toll-like receptor 3 signaling pathway IEA
 biological_processGO:0034346 positive regulation of type III interferon production IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0043330 response to exogenous dsRNA IEA
 biological_processGO:0045078 positive regulation of interferon-gamma biosynthetic process IEA
 biological_processGO:0045080 positive regulation of chemokine biosynthetic process IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045356 positive regulation of interferon-alpha biosynthetic process IEA
 biological_processGO:0045359 positive regulation of interferon-beta biosynthetic process IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046330 positive regulation of JNK cascade IEA
 biological_processGO:0050729 positive regulation of inflammatory response IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0071260 cellular response to mechanical stimulus IEA
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IEA
 biological_processGO:0097527 necroptotic signaling pathway IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003725 double-stranded RNA binding IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Trafficking and processing of endosomal TLR


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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