ENSDARG00000016065


Danio rerio

Features
Gene ID: ENSDARG00000016065
  
Biological name :tlr3
  
Synonyms : tlr3 / toll-like receptor 3
  
Possible biological names infered from orthology : Mus musculus toll-like receptor 3 (Tlr3), transcript variant 3, mRNA. / O15455 / Q99MB1
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 17892944
Gene end: 17898227
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000014779
NCBI entrez gene - 403126     See in Manteia.
RefSeq - NM_001013269
RefSeq Peptide - NP_001013287
swissprot - B8JIL3
ZFIN ID - ZDB-GENE-040219-7
Ensembl - ENSDARG00000016065
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TLR3ENSGALG00000013468Gallus gallus
 TLR3ENSG00000164342Homo sapiens
 Tlr3ENSMUSG00000031639Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TLR8 / toll like receptor 8 / Q9NR97*ENSDARG0000010483223
tlr7 / toll-like receptor 7 / Q9NYK1*ENSDARG0000006881223
tlr21 / toll-like receptor 21ENSDARG0000005804522
tlr22 / toll-like receptor 22ENSDARG0000010404522
tlr9 / toll-like receptor 9 / Q9NR96* / AC097637.1*ENSDARG0000004449022
tlr5b / toll-like receptor 5b / TLR5* / O60602* / toll like receptor 5*ENSDARG0000005232220
tlr5a / toll-like receptor 5a / TLR5* / O60602* / toll like receptor 5*ENSDARG0000004441520
tlr4al / toll-like receptor 4a, like / TLR4* / Q9QUK6* / O00206* / toll like receptor 4*ENSDARG0000007567119
tlr4ba / toll-like receptor 4b, duplicate a / TLR4* / Q9QUK6* / O00206* / toll like receptor 4*ENSDARG0000001974218
tlr18 / toll-like receptor 18ENSDARG0000004024918
tlr4bb / toll-like receptor 4b, duplicate b / TLR4* / Q9QUK6* / O00206* / toll like receptor 4*ENSDARG0000002204818
tlr1 / toll-like receptor 1 / TLR6* / TLR10* / Q15399* / Q9BXR5* / Q9EPQ1* / Q9Y2C9* / toll like receptor 6* / toll like receptor 10*ENSDARG0000010064917
tlr19 / toll-like receptor 19 / Tlr13* / Q6R5N8* / Toll-like receptor 13 *ENSDARG0000007039217
tlr20.2 / tlr20.4 / toll-like receptor 20, tandem duplicate 2 / Tlr13* / Q6R5N8* / Toll-like receptor 13 *ENSDARG0000008870117
tlr8b / toll-like receptor 8b / TLR8* / Q9NR97* / P58682* / toll like receptor 8*ENSDARG0000007367517
tlr19 / toll-like receptor 19 / Tlr13* / Q6R5N8* / Toll-like receptor 13 *ENSDARG0000002666317
tlr2 / toll-like receptor 2 / O60603*ENSDARG0000003775816
cd180 / CD180 molecule / Q62192* / Q99467* / CD180 antigen *ENSDARG0000009375013
senp7a / SUMO1/sentrin specific peptidase 7a / Tlr13* / Q6R5N8* / Toll-like receptor 13 *ENSDARG0000010952212
senp7a / SUMO1/sentrin specific peptidase 7a / Tlr13* / Q6R5N8* / Toll-like receptor 13 *ENSDARG0000011513611


Protein motifs (from Interpro)
Interpro ID Name
 IPR000157  Toll/interleukin-1 receptor homology (TIR) domain
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001819 positive regulation of cytokine production IEA
 biological_processGO:0002224 toll-like receptor signaling pathway IBA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002756 MyD88-independent toll-like receptor signaling pathway IEA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0009615 response to virus IDA
 biological_processGO:0009617 response to bacterium IDA
 biological_processGO:0032722 positive regulation of chemokine production IEA
 biological_processGO:0034138 toll-like receptor 3 signaling pathway IEA
 biological_processGO:0043330 response to exogenous dsRNA IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0050729 positive regulation of inflammatory response IEA
 biological_processGO:0051607 defense response to virus IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003725 double-stranded RNA binding IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Trafficking and processing of endosomal TLR


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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