ENSDARG00000100649


Danio rerio

Features
Gene ID: ENSDARG00000100649
  
Biological name :tlr1
  
Synonyms : tlr1 / toll-like receptor 1
  
Possible biological names infered from orthology : Q15399 / Q9BXR5 / Q9EPQ1 / Q9Y2C9 / TLR10 / TLR6 / toll like receptor 10 / toll like receptor 6
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 731864
Gene end: 736575
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000133513
Ensembl peptide - ENSDARP00000139386
NCBI entrez gene - 403127     See in Manteia.
RefSeq - NM_001130593
RefSeq Peptide - NP_001124065
swissprot - A0A0R4IW15
swissprot - A0A0R4IGC9
ZFIN ID - ZDB-GENE-040220-1
Ensembl - ENSDARG00000100649
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TLR1AENSGALG00000017485Gallus gallus
 TLR1BENSGALG00000027093Gallus gallus
 TLR1ENSG00000174125Homo sapiens
 TLR10ENSG00000174123Homo sapiens
 TLR6ENSG00000174130Homo sapiens
 Tlr1ENSMUSG00000044827Mus musculus
 Tlr6ENSMUSG00000051498Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tlr2 / toll-like receptor 2 / O60603*ENSDARG0000003775828
tlr18 / toll-like receptor 18ENSDARG0000004024927
tlr9 / toll-like receptor 9 / Q9NR96* / AC097637.1*ENSDARG0000004449021
tlr21 / toll-like receptor 21ENSDARG0000005804521
tlr5b / toll-like receptor 5b / TLR5* / O60602* / toll like receptor 5*ENSDARG0000005232220
tlr22 / toll-like receptor 22ENSDARG0000010404520
tlr5a / toll-like receptor 5a / TLR5* / O60602* / toll like receptor 5*ENSDARG0000004441520
tlr7 / toll-like receptor 7 / Q9NYK1*ENSDARG0000006881219
tlr3 / toll-like receptor 3 / O15455* / Q99MB1* / Mus musculus toll-like receptor 3 (Tlr3), transcript variant 3, mRNA.*ENSDARG0000001606519
TLR8 / toll like receptor 8 / Q9NR97*ENSDARG0000010483219
tlr4al / toll-like receptor 4a, like / TLR4* / Q9QUK6* / O00206* / toll like receptor 4*ENSDARG0000007567118
tlr4ba / toll-like receptor 4b, duplicate a / TLR4* / Q9QUK6* / O00206* / toll like receptor 4*ENSDARG0000001974218
tlr4bb / toll-like receptor 4b, duplicate b / TLR4* / Q9QUK6* / O00206* / toll like receptor 4*ENSDARG0000002204818
tlr19 / toll-like receptor 19 / Tlr13* / Q6R5N8* / Toll-like receptor 13 *ENSDARG0000007039217
tlr20.2 / tlr20.4 / toll-like receptor 20, tandem duplicate 2 / Tlr13* / Q6R5N8* / Toll-like receptor 13 *ENSDARG0000008870115
tlr19 / toll-like receptor 19 / Tlr13* / Q6R5N8* / Toll-like receptor 13 *ENSDARG0000002666315
tlr8b / toll-like receptor 8b / TLR8* / Q9NR97* / P58682* / toll like receptor 8*ENSDARG0000007367514
senp7a / SUMO1/sentrin specific peptidase 7a / Tlr13* / Q6R5N8* / Toll-like receptor 13 *ENSDARG0000010952212
senp7a / SUMO1/sentrin specific peptidase 7a / Tlr13* / Q6R5N8* / Toll-like receptor 13 *ENSDARG0000011513612
cd180 / CD180 molecule / Q62192* / Q99467* / CD180 antigen *ENSDARG0000009375011


Protein motifs (from Interpro)
Interpro ID Name
 IPR000157  Toll/interleukin-1 receptor homology (TIR) domain
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR027182  Toll-like receptor 10
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002755 MyD88-dependent toll-like receptor signaling pathway IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0034150 toll-like receptor 6 signaling pathway IEA
 biological_processGO:0042088 T-helper 1 type immune response IEA
 biological_processGO:0042496 detection of diacyl bacterial lipopeptide IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045410 positive regulation of interleukin-6 biosynthetic process IEA
 biological_processGO:0050707 regulation of cytokine secretion IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA


Pathways (from Reactome)
Pathway description
Toll Like Receptor 10 (TLR10) Cascade
Regulation of TLR by endogenous ligand


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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