ENSGALG00000014263


Gallus gallus

Features
Gene ID: ENSGALG00000014263
  
Biological name :PHC1
  
Synonyms : PHC1 / polyhomeotic-like protein 1
  
Possible biological names infered from orthology : Mus musculus polyhomeotic 1 (Phc1), transcript variant 5, mRNA. / P78364 / polyhomeotic homolog 1
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 76188197
Gene end: 76207347
  
Corresponding Affymetrix probe sets: GgaAffx.12255.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000062281
Ensembl peptide - ENSGALP00000023027
NCBI entrez gene - 418252     See in Manteia.
RefSeq - XM_015292601
RefSeq - NM_001006249
RefSeq - XM_015292595
RefSeq Peptide - NP_001006249
swissprot - F1NIT2
swissprot - A0A1L1RTY2
Ensembl - ENSGALG00000014263
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phc1ENSDARG00000002971Danio rerio
 PHC1ENSG00000111752Homo sapiens
 Phc1ENSMUSG00000040669Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PHC3* / Q8CHP6* / Q8NDX5* / polyhomeotic homolog 3* / Polyhomeotic-like protein 3 *ENSGALG0000000937229
SAMD11 / sterile alpha motif domain-containing protein 11 / Q1RNF8* / Q96NU1* / sterile alpha motif domain containing 11*ENSGALG0000003445310
PHC2* / Q8IXK0* / Q9QWH1* / polyhomeotic homolog 2* / Polyhomeotic-like protein 2 *ENSGALG000000395328
SAMD7 / sterile alpha motif domain containing 7 / Q7Z3H4* / Q8C8Y5* / Sterile alpha motif domain-containing protein 7 *ENSGALG000000093837


Protein motifs (from Interpro)
Interpro ID Name
 IPR001660  Sterile alpha motif domain
 IPR012313  Zinc finger, FCS-type
 IPR013761  Sterile alpha motif/pointed domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016574 histone ubiquitination IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0031519 PcG protein complex IEA
 cellular_componentGO:0035102 PRC1 complex IEA
 molecular_functionGO:0008270 zinc ion binding IEA


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000041267 BMI1 / Q5SDR3 / Polycomb complex protein BMI-1 / P25916* / P35226* / COMMD3-BMI1* / COMMD3-BMI1 readthrough* / BMI1 proto-oncogene, polycomb ring finger*  / complex
 ENSGALG00000018815 PCGF2 / P23798* / P35227* / polycomb group ring finger 2* / Polycomb group RING finger protein 2 *  / complex






 

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