ENSGALG00000014362


Gallus gallus

Features
Gene ID: ENSGALG00000014362
  
Biological name :CD86
  
Synonyms : CD86 / CD86 molecule
  
Possible biological names infered from orthology : P42081 / P42082 / T-lymphocyte activation antigen CD86
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 76641354
Gene end: 76652029
  
Corresponding Affymetrix probe sets: GgaAffx.9118.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000036384
NCBI entrez gene - 427944     See in Manteia.
RefSeq - NM_001037839
RefSeq - XM_015293509
RefSeq Peptide - NP_001032928
swissprot - Q3BKZ5
Ensembl - ENSGALG00000014362
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CD86ENSG00000114013Homo sapiens
 Cd86ENSMUSG00000022901Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CD80 / T-lymphocyte activation antigen CD80 precursor / P33681* / Q00609* / CD80 molecule* / T-lymphocyte activation antigen CD80 *ENSGALG0000001547423


Protein motifs (from Interpro)
Interpro ID Name
 IPR007110  Immunoglobulin-like domain
 IPR013162  CD80-like, immunoglobulin C2-set
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome IEA


Pathways (from Reactome)
Pathway description
PIP3 activates AKT signaling
CD28 co-stimulation
CD28 dependent PI3K/Akt signaling
CD28 dependent Vav1 pathway
CTLA4 inhibitory signaling
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008669 CD28 / P31043 / T-cell-specific surface glycoprotein CD28 homolog / P31041* / P10747* / CD28 molecule* / T-cell-specific surface glycoprotein CD28 *  / complex / reaction
 ENSGALG00000008016 GRB2 / growth factor receptor-bound protein 2 / P62993* / Q60631*  / reaction / complex
 ENSGALG00000015022 FYN / tyrosine-protein kinase Fyn / P06241* / P39688* / FYN proto-oncogene, Src family tyrosine kinase*  / reaction / complex
 ENSGALG00000004796 CDC42 / Q90694 / Cell division control protein 42 homolog / P60766* / P60953* / cell division cycle 42* / Cell division control *  / reaction
 ENSGALG00000008934 PIK3CA / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha / P42336* / P42337* / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform *  / complex / reaction
 ENSGALG00000008666 CTLA4 / cytotoxic T-lymphocyte associated protein 4 / P16410*  / complex / reaction
 ENSGALG00000004821 PTPN11 / Q90687 / Tyrosine-protein phosphatase non-receptor type 11 / P35235* / Q06124* / protein tyrosine phosphatase, non-receptor type 11*  / complex / reaction
 ENSGALG00000007130 RAC1 / Rac family small GTPase 1 / P63000* / P63001* / RAS-related C3 botulinum substrate 1*  / reaction
 ENSGALG00000000466 LCK / LCK proto-oncogene, Src family tyrosine kinase / P06239* / P06240* / Proto-onco tyrosine-protein kinase LCK *  / complex / reaction
 ENSGALG00000014786 PIK3R1 / phosphoinositide-3-kinase regulatory subunit 1 / P26450* / P27986*  / reaction / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr