ENSGALG00000014732


Gallus gallus

Features
Gene ID: ENSGALG00000014732
  
Biological name :ERCC8
  
Synonyms : ERCC8 / ERCC excision repair 8, CSA ubiquitin ligase complex subunit
  
Possible biological names infered from orthology : DNA excision repair protein ERCC-8 / Q13216 / Q8CFD5
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 18932816
Gene end: 18970473
  
Corresponding Affymetrix probe sets: Gga.11058.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000023709
Ensembl peptide - ENSGALP00000055615
Ensembl peptide - ENSGALP00000047145
NCBI entrez gene - 427153     See in Manteia.
RefSeq - XM_015277594
RefSeq - XM_424742
swissprot - E1C100
swissprot - A0A1D5PRT7
swissprot - A0A1D5P390
Ensembl - ENSGALG00000014732
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ercc8ENSDARG00000069283Danio rerio
 ERCC8ENSG00000049167Homo sapiens
 Ercc8ENSMUSG00000021694Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IEA
 biological_processGO:0006283 transcription-coupled nucleotide-excision repair IEA
 biological_processGO:0006289 nucleotide-excision repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0009411 response to UV IEA
 biological_processGO:0010165 response to X-ray IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0051865 protein autoubiquitination IEA
 cellular_componentGO:0000109 nucleotide-excision repair complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016363 nuclear matrix IEA
 cellular_componentGO:0031464 Cul4A-RING E3 ubiquitin ligase complex IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0080008 Cul4-RING E3 ubiquitin ligase complex IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA


Pathways (from Reactome)
Pathway description
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000006254 ERCC6 / ERCC excision repair 6, chromatin remodeling factor / P0DP91* / Q03468* / Q8N328*  / complex / reaction
 ENSGALG00000011993 RBX1 / ring-box 1 / P62877* / P62878* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed*  / complex
 ENSGALG00000008559 CUL4B / cullin 4B / A2A432* / Q13620*  / complex
 ENSGALG00000042333 DDB1 / Q805F9 / DNA damage-binding protein 1 / Q16531* / Q3U1J4* / damage specific DNA binding protein 1*  / complex
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex / reaction






 

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