ENSGALG00000006254


Gallus gallus

Features
Gene ID: ENSGALG00000006254
  
Biological name :ERCC6
  
Synonyms : ERCC6 / ERCC excision repair 6, chromatin remodeling factor
  
Possible biological names infered from orthology : P0DP91 / Q03468 / Q8N328
  
Species: Gallus gallus
  
Chr. number: 6
Strand: -1
Band:
Gene start: 18735599
Gene end: 18779135
  
Corresponding Affymetrix probe sets: Gga.10777.1.S1_s_at (Chicken Array)   Gga.1358.1.S1_at (Chicken Array)   GgaAffx.21880.1.S1_s_at (Chicken Array)   GgaAffx.3892.1.S1_at (Chicken Array)   GgaAffx.3892.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010093
NCBI entrez gene - 423785     See in Manteia.
RefSeq - XM_004942139
RefSeq - XM_421656
RefSeq - XM_004942140
RefSeq - XM_015288418
swissprot - E1BYA8
Ensembl - ENSGALG00000006254
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ercc6ENSDARG00000075612Danio rerio
 ERCC6ENSG00000225830Homo sapiens
 Ercc6ENSMUSG00000054051Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ERCC6L / ERCC excision repair 6 like, spindle assembly checkpoint helicase / Q2NKX8* / Q8BHK9* / DNA excision repair protein ERCC-6-like *ENSGALG0000000388117


Protein motifs (from Interpro)
Interpro ID Name
 IPR000330  SNF2-related, N-terminal domain
 IPR001650  Helicase, C-terminal
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000303 response to superoxide IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006283 transcription-coupled nucleotide-excision repair IEA
 biological_processGO:0006284 base-excision repair IEA
 biological_processGO:0006290 pyrimidine dimer repair IEA
 biological_processGO:0006362 transcription elongation from RNA polymerase I promoter IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0007256 activation of JNKK activity IEA
 biological_processGO:0007257 activation of JUN kinase activity IEA
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IEA
 biological_processGO:0009411 response to UV IEA
 biological_processGO:0009636 response to toxic substance IEA
 biological_processGO:0010165 response to X-ray IEA
 biological_processGO:0010224 response to UV-B IEA
 biological_processGO:0010332 response to gamma radiation IEA
 biological_processGO:0032784 regulation of DNA-templated transcription, elongation IEA
 biological_processGO:0032786 positive regulation of DNA-templated transcription, elongation IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0045494 photoreceptor cell maintenance IEA
 biological_processGO:0061098 positive regulation of protein tyrosine kinase activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0008023 transcription elongation factor complex IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0008094 DNA-dependent ATPase activity IEA
 molecular_functionGO:0030296 protein tyrosine kinase activator activity IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0047485 protein N-terminus binding IEA


Pathways (from Reactome)
Pathway description
B-WICH complex positively regulates rRNA expression
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
RNA Polymerase I Transcription Initiation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008559 CUL4B / cullin 4B / A2A432* / Q13620*  / reaction / complex
 ENSGALG00000011993 RBX1 / ring-box 1 / P62877* / P62878* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed*  / complex / reaction
 ENSGALG00000006254 ERCC6 / ERCC excision repair 6, chromatin remodeling factor / P0DP91* / Q03468* / Q8N328*  / complex
 ENSGALG00000042333 DDB1 / Q805F9 / DNA damage-binding protein 1 / Q16531* / Q3U1J4* / damage specific DNA binding protein 1*  / complex / reaction
 ENSGALG00000014732 ERCC8 / ERCC excision repair 8, CSA ubiquitin ligase complex subunit / Q13216* / Q8CFD5* / DNA excision repair protein ERCC-8 *  / complex / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction / complex






 

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