ENSDARG00000075612


Danio rerio

Features
Gene ID: ENSDARG00000075612
  
Biological name :ercc6
  
Synonyms : ercc6 / excision repair cross-complementation group 6
  
Possible biological names infered from orthology : ERCC excision repair 6, chromatin remodeling factor / P0DP91 / Q03468 / Q8N328
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 30874153
Gene end: 30910016
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000099262
Ensembl peptide - ENSDARP00000119156
Ensembl peptide - ENSDARP00000151165
Ensembl peptide - ENSDARP00000152481
swissprot - F1R294
swissprot - F1RDN1
ZFIN ID - ZDB-GENE-070228-1
Ensembl - ENSDARG00000075612
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ERCC6ENSGALG00000006254Gallus gallus
 ERCC6ENSG00000225830Homo sapiens
 Ercc6ENSMUSG00000054051Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A2BGR3 / ercc6l / excision repair cross-complementation group 6-like / Q8BHK9* / Q2NKX8* / DNA excision repair protein ERCC-6-like * / ERCC excision repair 6 like, spindle assembly checkpoi...ENSDARG0000000247917
ercc6l2 / excision repair cross-complementation group 6-like 2 / Q5T890* / Q9JIM3* / ERCC excision repair 6 like 2* / DNA excision repair protein ERCC-6-like 2 *ENSDARG0000001240317


Protein motifs (from Interpro)
Interpro ID Name
 IPR000330  SNF2-related, N-terminal domain
 IPR001650  Helicase, C-terminal
 IPR011991  ArsR-like helix-turn-helix domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006974 cellular response to DNA damage stimulus IMP
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
B-WICH complex positively regulates rRNA expression
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
RNA Polymerase I Transcription Initiation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001114 head head decreased size , abnormal
head hydrocephalic , abnormal
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 ZFA:0001115 trunk trunk decreased size , abnormal
trunk malformed , abnormal
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 ZFA:0001117 post-vent region post-vent region curved , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000060510 cul4b / cullin 4B / A2A432* / Q13620*  / reaction / complex
 ENSDARG00000038030 rbx1 / ring-box 1, E3 ubiquitin protein ligase / P62878* / P62877* / ring-box 1* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed*  / reaction / complex
 ENSDARG00000096578 cul4a / cullin 4A / Q13619* / Q3TCH7*  / complex / reaction
 ENSDARG00000075612 ercc6 / excision repair cross-complementation group 6 / P0DP91* / Q03468* / Q8N328* / ERCC excision repair 6, chromatin remodeling factor*  / complex






 

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