ENSGALG00000014795


Gallus gallus

Features
Gene ID: ENSGALG00000014795
  
Biological name :TGIF1
  
Synonyms : Homeobox protein AKR / Q90655 / TGIF1
  
Possible biological names infered from orthology : P70284 / Q15583 / TGFB induced factor homeobox 1
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 101084414
Gene end: 101092939
  
Corresponding Affymetrix probe sets: Gga.768.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044592
Ensembl peptide - ENSGALP00000054900
Ensembl peptide - ENSGALP00000023838
NCBI entrez gene - 396339     See in Manteia.
RefSeq - NM_205379
RefSeq Peptide - NP_990710
swissprot - A0A1D5NW56
swissprot - Q90655
Ensembl - ENSGALG00000014795
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tgif1ENSDARG00000059337Danio rerio
 TGIF1ENSG00000177426Homo sapiens
 Tgif1ENSMUSG00000047407Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TGIF2 / TGFB induced factor homeobox 2 / Q8C0Y1* / Q9GZN2*ENSGALG0000002408145
PKNOX2 / PBX/knotted 1 homeobox 2 / Q8BG99* / Q96KN3* / Homeobox protein PKNOX2 *ENSGALG0000004310318
PKNOX1 / PBX/knotted 1 homeobox 1 / O70477* / P55347* / Homeobox protein PKNOX1 *ENSGALG0000001619118
MEIS1 / homeobox protein Meis1 / O00470* / Q60954* / Meis homeobox 1*ENSGALG0000004162617
MEIS2 / homeobox protein Meis2 / O14770* / P97367* / Meis homeobox 2*ENSGALG0000003911817


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR008422  Homeobox KN domain
 IPR009057  Homeobox-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
Downregulation of SMAD2/3:SMAD4 transcriptional activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003297 HDAC1 / P56517 / Histone deacetylase 1 / O09106* / Q13547* / Gm10093*  / complex / reaction
 ENSGALG00000036001 SMAD2Z / SMAD2* / Q62432* / Q15796* / SMAD family member 2* / Mothers against decapentaplegic homolog 2 *  / complex / reaction
 ENSGALG00000014184 SMAD2* / Q15796* / Q62432* / SMAD family member 2* / Mothers against decapentaplegic homolog 2 *  / reaction / complex






 

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