ENSGALG00000024081


Gallus gallus

Features
Gene ID: ENSGALG00000024081
  
Biological name :TGIF2
  
Synonyms : TGFB induced factor homeobox 2 / TGIF2
  
Possible biological names infered from orthology : Q8C0Y1 / Q9GZN2
  
Species: Gallus gallus
  
Chr. number: 20
Strand: -1
Band:
Gene start: 481571
Gene end: 486410
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000049037
Ensembl peptide - ENSGALP00000030301
NCBI entrez gene - 428131     See in Manteia.
RefSeq - XM_015296287
RefSeq - XM_015296288
RefSeq - XM_015296289
RefSeq - XM_015296285
RefSeq - XM_015296286
swissprot - F1NHZ2
Ensembl - ENSGALG00000024081
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FO834857.1ENSDARG00000112895Danio rerio
 TGIF2ENSG00000118707Homo sapiens
 Tgif2ENSMUSG00000062175Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TGIF1 / Q90655 / Homeobox protein AKR / Q15583* / P70284* / TGFB induced factor homeobox 1*ENSGALG0000001479546
PKNOX2 / PBX/knotted 1 homeobox 2 / Q8BG99* / Q96KN3* / Homeobox protein PKNOX2 *ENSGALG0000004310318
PKNOX1 / PBX/knotted 1 homeobox 1 / O70477* / P55347* / Homeobox protein PKNOX1 *ENSGALG0000001619117
MEIS2 / homeobox protein Meis2 / O14770* / P97367* / Meis homeobox 2*ENSGALG0000003911816
MEIS1 / homeobox protein Meis1 / O00470* / Q60954* / Meis homeobox 1*ENSGALG0000004162615


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR008422  Homeobox KN domain
 IPR009057  Homeobox-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0010470 regulation of gastrulation IEA
 biological_processGO:0038092 nodal signaling pathway IEA
 biological_processGO:0045666 positive regulation of neuron differentiation IEA
 biological_processGO:0060041 retina development in camera-type eye IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
Downregulation of SMAD2/3:SMAD4 transcriptional activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003297 HDAC1 / P56517 / Histone deacetylase 1 / O09106* / Q13547* / Gm10093*  / complex / reaction
 ENSGALG00000036001 SMAD2Z / SMAD2* / Q62432* / Q15796* / SMAD family member 2* / Mothers against decapentaplegic homolog 2 *  / complex / reaction
 ENSGALG00000014184 SMAD2* / Q15796* / Q62432* / SMAD family member 2* / Mothers against decapentaplegic homolog 2 *  / reaction / complex






 

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