ENSGALG00000014855


Gallus gallus

Features
Gene ID: ENSGALG00000014855
  
Biological name :GHR
  
Synonyms : GHR / growth hormone receptor precursor
  
Possible biological names infered from orthology : growth hormone receptor / Growth hormone receptor Growth hormone-binding protein / P10912 / P16882
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 13428436
Gene end: 13558478
  
Corresponding Affymetrix probe sets: Gga.4329.1.S1_at (Chicken Array)   Gga.4329.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046304
Ensembl peptide - ENSGALP00000056377
Ensembl peptide - ENSGALP00000023927
NCBI entrez gene - 408184     See in Manteia.
RefSeq - NM_001001293
RefSeq Peptide - NP_001001293
swissprot - A0A1D5NVR2
swissprot - F1N9U3
Ensembl - ENSGALG00000014855
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ghraENSDARG00000054771Danio rerio
 ghrbENSDARG00000007671Danio rerio
 GHRENSG00000112964Homo sapiens
 GhrENSMUSG00000055737Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRLR / prolactin receptor precursor / P16471* / Q08501* / Gm21973* / prolactin receptor*ENSGALG0000000344621
CRLF1 / cytokine receptor like factor 1 / O75462* / Q9JM58*ENSGALG000000261469


Protein motifs (from Interpro)
Interpro ID Name
 IPR003528  Long hematopoietin receptor, single chain, conserved site
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR015152  Growth hormone/erythropoietin receptor, ligand binding
 IPR025871  Growth hormone-binding protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019221 cytokine-mediated signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004896 cytokine receptor activity IEA


Pathways (from Reactome)
Pathway description
Prolactin receptor signaling
Growth hormone receptor signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000249 GH / P08998 / Somatotropin / GH2* / GH1* / CSH1* / CSH2* / CSHL1* / Q14406* / P0DML3* / P0DML2* / P01241* / P01242* / P06880* / growth hormone 1* / growth hormone 2* / chorionic somatomamm...  / reaction / complex
 ENSGALG00000008010 PTPN1 / tyrosine-protein phosphatase non-receptor type 1 / P18031* / P35821* / protein tyrosine phosphatase, non-receptor type 1*  / reaction / complex
 ENSGALG00000003282 STAT5B / signal transducer and activator of transcription 5B / P42229* / P42232* / P51692* / P42230* / STAT5A* / signal transducer and activator of transcription 5A*  / complex
 ENSGALG00000014855 GHR / growth hormone receptor precursor / P16882* / P10912* / growth hormone receptor* / Growth hormone receptor Growth hormone-binding protein*  / reaction / complex
 ENSGALG00000015027 JAK2 / Janus kinase 2 / O60674*  / complex / reaction
 ENSGALG00000042321 LYN / LYN proto-oncogene, Src family tyrosine kinase / P07948* / P25911*  / complex






 

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