ENSGALG00000015624


Gallus gallus

Features
Gene ID: ENSGALG00000015624
  
Biological name :VCAN
  
Synonyms : VCAN / versican core protein precursor
  
Possible biological names infered from orthology : P13611 / versican
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 62650853
Gene end: 62756712
  
Corresponding Affymetrix probe sets: Gga.4974.1.S1_at (Chicken Array)   Gga.4974.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000025144
NCBI entrez gene - 395565     See in Manteia.
RefSeq - XM_015280586
RefSeq - NM_204787
RefSeq - XM_015280584
RefSeq - XM_015280585
RefSeq Peptide - NP_990118
swissprot - E1BZM6
Ensembl - ENSGALG00000015624
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vcanaENSDARG00000103515Danio rerio
 vcanbENSDARG00000009401Danio rerio
 VCANENSG00000038427Homo sapiens
 VcanENSMUSG00000021614Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ACAN / Q61282* / aggrecan* / Aggrecan core protein *ENSGALG0000000672512
NCAN / neurocan core protein precursor / O14594* / neurocan*ENSGALG0000003648410
BCAN / brevican / Q61361* / Q96GW7* / Brevican core protein *ENSGALG000000454699
STAB1 / stabilin 1 / Q9NY15*ENSGALG000000436725
HAPLN2 / hyaluronan and proteoglycan link protein 2 / Q9ESM3* / Q9GZV7*ENSGALG000000132343
HAPLN3 / hyaluronan and proteoglycan link protein 3 / Q80WM5* / Q96S86*ENSGALG000000211353
HAPLN4 / hyaluronan and proteoglycan link protein 4 / Q80WM4* / Q86UW8*ENSGALG000000265633
HAPLN1 / P07354 / Hyaluronan and proteoglycan link protein 1 / P10915* / Q9QUP5*ENSGALG000000156273
TNFAIP6 / TNF alpha induced protein 6 / O08859* / P98066* / tumor necrosis factor alpha induced protein 6*ENSGALG000000124812
ENSGALG000000392452
ENSGALG000000298241
ENSGALG000000413601


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000436  Sushi/SCR/CCP domain
 IPR000538  Link domain
 IPR000742  EGF-like domain
 IPR001304  C-type lectin-like
 IPR001881  EGF-like calcium-binding domain
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013032  EGF-like, conserved site
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018097  EGF-like calcium-binding, conserved site
 IPR018378  C-type lectin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005540 hyaluronic acid binding IEA


Pathways (from Reactome)
Pathway description
A tetrasaccharide linker sequence is required for GAG synthesis
Chondroitin sulfate biosynthesis
Dermatan sulfate biosynthesis
CS/DS degradation
ECM proteoglycans
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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