ENSDARG00000103515


Danio rerio

Features
Gene ID: ENSDARG00000103515
  
Biological name :vcana
  
Synonyms : vcana / versican a
  
Possible biological names infered from orthology : P13611 / VCAN / versican
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 46424437
Gene end: 46486028
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000119809
Ensembl peptide - ENSDARP00000147274
NCBI entrez gene - 116993     See in Manteia.
RefSeq - NM_001326557
RefSeq Peptide - NP_001313486
swissprot - Q1LXE5
ZFIN ID - ZDB-GENE-011023-1
Ensembl - ENSDARG00000103515
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 VCANENSGALG00000015624Gallus gallus
 VCANENSG00000038427Homo sapiens
 VcanENSMUSG00000021614Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
vcanb / versican b / VCAN* / P13611* / versican*ENSDARG0000000940162
ncanb / neurocan b / NCAN* / O14594* / neurocan*ENSDARG0000000578349
acana / aggrecan a / ACAN* / Q61282* / aggrecan* / Aggrecan core protein *ENSDARG0000003589145
bcan / brevican / Q61361* / Q96GW7* / Brevican core protein *ENSDARG0000009941243
acanb / aggrecan b / ACAN* / Q61282* / aggrecan* / Aggrecan core protein *ENSDARG0000004579941
CU861477.1 / NCAN* / O14594* / neurocan*ENSDARG0000010012823
stab2 / stabilin 2 / Q8R4U0* / Q8WWQ8* / Stabilin-2 Short form stabilin-2*ENSDARG0000004574821
hapln2 / hyaluronan and proteoglycan link protein 2 / Q9ESM3* / Q9GZV7*ENSDARG0000000390319
hapln1b / hyaluronan and proteoglycan link protein 1b / Q9QUP5* / HAPLN1* / P10915* / hyaluronan and proteoglycan link protein 1*ENSDARG0000006851619
stab1 / stabilin 1 / Q9NY15*ENSDARG0000007648419
hapln3 / hyaluronan and proteoglycan link protein 3 / Q80WM5* / Q96S86*ENSDARG0000004580219
hapln1a / hyaluronan and proteoglycan link protein 1aENSDARG0000008976919
hapln4 / hyaluronan and proteoglycan link protein 4 / Q80WM4* / Q86UW8*ENSDARG0000001854219
tnfaip6 / tumor necrosis factor, alpha-induced protein 6 / O08859* / P98066* / TNF alpha induced protein 6*ENSDARG0000009344010


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000436  Sushi/SCR/CCP domain
 IPR000538  Link domain
 IPR000742  EGF-like domain
 IPR001304  C-type lectin-like
 IPR001881  EGF-like calcium-binding domain
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013032  EGF-like, conserved site
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018097  EGF-like calcium-binding, conserved site
 IPR018378  C-type lectin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003093 regulation of glomerular filtration IMP
 biological_processGO:0003203 endocardial cushion morphogenesis IMP
 biological_processGO:0035775 pronephric glomerulus morphogenesis IMP


Pathways (from Reactome)
Pathway description
A tetrasaccharide linker sequence is required for GAG synthesis
Chondroitin sulfate biosynthesis
Dermatan sulfate biosynthesis
CS/DS degradation
ECM proteoglycans
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood protein decreased amount , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0001315 atrioventricular canal atrioventricular canal absent , abnormal
atrioventricular canal increased distribution , abnormal
Show

 ZFA:0001317 endocardial cushion endocardial cushion morphology , abnormal
Show

 ZFA:0001557 pronephric glomerulus pronephric glomerulus lacks parts or has fewer parts of type glomerular basement membrane glomerular endothelium fenestra, abnormal
Show

 ZFA:0001673 pronephric podocyte pronephric podocyte decreased length , abnormal
pronephric podocyte increased width , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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