ENSDARG00000045748


Danio rerio

Features
Gene ID: ENSDARG00000045748
  
Biological name :stab2
  
Synonyms : stab2 / stabilin 2
  
Possible biological names infered from orthology : Q8R4U0 / Q8WWQ8 / Stabilin-2 Short form stabilin-2
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 10721795
Gene end: 10763547
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000116540
Ensembl peptide - ENSDARP00000067252
Ensembl peptide - ENSDARP00000146807
NCBI entrez gene - 565194     See in Manteia.
RefSeq - NM_001290178
RefSeq - XM_017355051
RefSeq Peptide - NP_001277107
swissprot - F6P8Y7
swissprot - E7EYE0
ZFIN ID - ZDB-GENE-041210-336
Ensembl - ENSDARG00000045748
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 STAB2ENSG00000136011Homo sapiens
 Stab2ENSMUSG00000035459Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
stab1 / stabilin 1 / Q9NY15*ENSDARG0000007648437
acana / aggrecan a / ACAN* / Q61282* / aggrecan* / Aggrecan core protein *ENSDARG000000358917
acanb / aggrecan b / ACAN* / Q61282* / aggrecan* / Aggrecan core protein *ENSDARG000000457996
ncanb / neurocan b / NCAN* / O14594* / neurocan*ENSDARG000000057836
vcanb / versican b / VCAN* / P13611* / versican*ENSDARG000000094016
vcana / versican a / VCAN* / P13611* / versican*ENSDARG000001035155
bcan / brevican / Q61361* / Q96GW7* / Brevican core protein *ENSDARG000000994125
CU861477.1 / NCAN* / O14594* / neurocan*ENSDARG000001001283
hapln3 / hyaluronan and proteoglycan link protein 3 / Q80WM5* / Q96S86*ENSDARG000000458023
hapln1a / hyaluronan and proteoglycan link protein 1aENSDARG000000897692
hapln4 / hyaluronan and proteoglycan link protein 4 / Q80WM4* / Q86UW8*ENSDARG000000185422
hapln1b / hyaluronan and proteoglycan link protein 1b / Q9QUP5* / HAPLN1* / P10915* / hyaluronan and proteoglycan link protein 1*ENSDARG000000685162
hapln2 / hyaluronan and proteoglycan link protein 2 / Q9ESM3* / Q9GZV7*ENSDARG000000039032
tnfaip6 / tumor necrosis factor, alpha-induced protein 6 / O08859* / P98066* / TNF alpha induced protein 6*ENSDARG000000934401


Protein motifs (from Interpro)
Interpro ID Name
 IPR000538  Link domain
 IPR000742  EGF-like domain
 IPR000782  FAS1 domain
 IPR001881  EGF-like calcium-binding domain
 IPR002049  Laminin EGF domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR024731  EGF domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001568 blood vessel development IMP
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0060837 blood vessel endothelial cell differentiation IMP
 biological_processGO:1901492 positive regulation of lymphangiogenesis IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005540 hyaluronic acid binding IEA


Pathways (from Reactome)
Pathway description
Hyaluronan uptake and degradation
Scavenging by Class H Receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001285 intersegmental vessel intersegmental vessel absent , abnormal
Show

 ZFA:0005110 thoracic duct thoracic duct hypoplastic , abnormal
Show

 ZFA:0009395 vascular lymphangioblast vascular lymphangioblast hypoplastic , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000059931 hyal2a / hyaluronoglucosaminidase 2a / HYAL2* / Q12891* / O35632* / Hyaluronidase-2 * / hyaluronoglucosaminidase 2*  / complex / reaction
 ENSDARG00000062997 hyal2b / hyaluronoglucosaminidase 2b / HYAL2* / Q12891* / O35632* / Hyaluronidase-2 * / hyaluronoglucosaminidase 2*  / complex / reaction
 ENSDARG00000052859 chp1 / calcineurin-like EF-hand protein 1 / P61022* / Q99653* / Calcineurin B homologous protein 1 *  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr