ENSGALG00000025748


Gallus gallus

Features
Gene ID: ENSGALG00000025748
  
Biological name :FGF9
  
Synonyms : FGF9 / fibroblast growth factor 9
  
Possible biological names infered from orthology : P31371 / P54130
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 178382192
Gene end: 178412065
  
Corresponding Affymetrix probe sets: Gga.8489.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000041598
NCBI entrez gene - 378917     See in Manteia.
RefSeq - NM_204399
RefSeq Peptide - NP_989730
swissprot - Q7ZZN4
Ensembl - ENSGALG00000025748
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FGF9ENSG00000102678Homo sapiens
 Fgf9ENSMUSG00000021974Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FGF20 / fibroblast growth factor 20 / Q9ESL9* / Q9NP95*ENSGALG0000001366373
FGF16 / fibroblast growth factor 16 / O43320* / Q9ESL8*ENSGALG0000000780671
FGF3 / P48801 / Fibroblast growth factor 3 / P11487*ENSGALG0000002685335
FGF13 / fibroblast growth factor 13 / P70377* / Q92913* / Mus musculus fibroblast growth factor 13 (Fgf13), transcript variant 4, mRNA.*ENSGALG0000000650832
FGF10 / fibroblast growth factor 10 / O15520* / O35565*ENSGALG0000001487230
FGF22 / fibroblast growth factor 22 / Q9ESS2* / Q9HCT0*ENSGALG0000004182230
FGF12 / fibroblast growth factor 12 / P61328* / P61329*ENSGALG0000003697130
FGF6 / fibroblast growth factor 6 / P10767* / P21658*ENSGALG0000001728729
FGF7 / fibroblast growth factor 7 / P21781* / P36363*ENSGALG0000002815829
FGF14 / fibroblast growth factor 14 / Q92915*ENSGALG0000001686629
FGF4 / fibroblast growth factor 4 precursor / P08620* / P11403* / fibroblast growth factor 4*ENSGALG0000000756228
FGF5 / fibroblast growth factor 5 / P12034* / P15656*ENSGALG0000004552125


Protein motifs (from Interpro)
Interpro ID Name
 IPR002209  Fibroblast growth factor family
 IPR008996  Cytokine IL1/FGF
 IPR028251  Fibroblast growth factor 9


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001649 osteoblast differentiation ISA
 biological_processGO:0001654 eye development IEA
 biological_processGO:0002053 positive regulation of mesenchymal cell proliferation ISA
 biological_processGO:0002062 chondrocyte differentiation IEA
 biological_processGO:0006606 protein import into nucleus ISA
 biological_processGO:0007267 cell-cell signaling ISA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway ISA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0021762 substantia nigra development ISA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway ISA
 biological_processGO:0030238 male sex determination ISA
 biological_processGO:0030324 lung development ISA
 biological_processGO:0030326 embryonic limb morphogenesis IEA
 biological_processGO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway ISA
 biological_processGO:0032927 positive regulation of activin receptor signaling pathway ISA
 biological_processGO:0042472 inner ear morphogenesis IEA
 biological_processGO:0045880 positive regulation of smoothened signaling pathway ISA
 biological_processGO:0048505 regulation of timing of cell differentiation ISA
 biological_processGO:0048566 embryonic digestive tract development IEA
 biological_processGO:0048706 embryonic skeletal system development ISA
 biological_processGO:0050679 positive regulation of epithelial cell proliferation IEA
 biological_processGO:0060045 positive regulation of cardiac muscle cell proliferation ISA
 biological_processGO:0060484 lung-associated mesenchyme development ISA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:1904707 positive regulation of vascular smooth muscle cell proliferation IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0070062 extracellular exosome ISA
 molecular_functionGO:0005104 fibroblast growth factor receptor binding IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
PI3K Cascade
PIP3 activates AKT signaling
FGFR4 ligand binding and activation
FGFR3b ligand binding and activation
FGFR3c ligand binding and activation
FGFR1c ligand binding and activation
FGFR2c ligand binding and activation
Phospholipase C-mediated cascade: FGFR1
Phospholipase C-mediated cascade; FGFR2
Phospholipase C-mediated cascade; FGFR3
Phospholipase C-mediated cascade; FGFR4
Downstream signaling of activated FGFR1
SHC-mediated cascade:FGFR1
PI-3K cascade:FGFR1
FRS-mediated FGFR1 signaling
PI-3K cascade:FGFR2
SHC-mediated cascade:FGFR2
FRS-mediated FGFR2 signaling
SHC-mediated cascade:FGFR3
FRS-mediated FGFR3 signaling
PI-3K cascade:FGFR3
FRS-mediated FGFR4 signaling
SHC-mediated cascade:FGFR4
PI-3K cascade:FGFR4
Negative regulation of FGFR1 signaling
Negative regulation of FGFR2 signaling
Negative regulation of FGFR3 signaling
Negative regulation of FGFR4 signaling
RAF/MAP kinase cascade
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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