ENSGALG00000028158


Gallus gallus

Features
Gene ID: ENSGALG00000028158
  
Biological name :FGF7
  
Synonyms : FGF7 / fibroblast growth factor 7
  
Possible biological names infered from orthology : P21781 / P36363
  
Species: Gallus gallus
  
Chr. number: 10
Strand: 1
Band:
Gene start: 10538345
Gene end: 10565443
  
Corresponding Affymetrix probe sets: Gga.11317.1.S1_at (Chicken Array)   Gga.11317.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000042868
NCBI entrez gene - 415439     See in Manteia.
RefSeq - XM_015291989
RefSeq - NM_001012525
RefSeq - XM_015291986
RefSeq - XM_015291987
RefSeq - XM_015291985
RefSeq Peptide - NP_001012543
swissprot - Q5KRA4
Ensembl - ENSGALG00000028158
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fgf7ENSDARG00000059387Danio rerio
 FGF7ENSG00000140285Homo sapiens
 Fgf7ENSMUSG00000027208Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FGF10 / fibroblast growth factor 10 / O15520* / O35565*ENSGALG0000001487244
FGF22 / fibroblast growth factor 22 / Q9ESS2* / Q9HCT0*ENSGALG0000004182241
FGF3 / P48801 / Fibroblast growth factor 3 / P11487*ENSGALG0000002685335
FGF20 / fibroblast growth factor 20 / Q9ESL9* / Q9NP95*ENSGALG0000001366333
FGF16 / fibroblast growth factor 16 / O43320* / Q9ESL8*ENSGALG0000000780633
FGF9 / fibroblast growth factor 9 / P31371* / P54130*ENSGALG0000002574831
FGF4 / fibroblast growth factor 4 precursor / P08620* / P11403* / fibroblast growth factor 4*ENSGALG0000000756227
FGF6 / fibroblast growth factor 6 / P10767* / P21658*ENSGALG0000001728727
FGF13 / fibroblast growth factor 13 / P70377* / Q92913* / Mus musculus fibroblast growth factor 13 (Fgf13), transcript variant 4, mRNA.*ENSGALG0000000650825
FGF12 / fibroblast growth factor 12 / P61328* / P61329*ENSGALG0000003697125
FGF14 / fibroblast growth factor 14 / Q92915*ENSGALG0000001686624
FGF5 / fibroblast growth factor 5 / P12034* / P15656*ENSGALG0000004552121


Protein motifs (from Interpro)
Interpro ID Name
 IPR002209  Fibroblast growth factor family
 IPR008996  Cytokine IL1/FGF
 IPR028247  Fibroblast growth factor 7


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway IEA
 biological_processGO:0010463 mesenchymal cell proliferation IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010838 positive regulation of keratinocyte proliferation IEA
 biological_processGO:0031069 hair follicle morphogenesis IEA
 biological_processGO:0031532 actin cytoskeleton reorganization IEA
 biological_processGO:0034394 protein localization to cell surface IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0050679 positive regulation of epithelial cell proliferation IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0050918 positive chemotaxis IEA
 biological_processGO:0051549 positive regulation of keratinocyte migration IEA
 biological_processGO:0060445 branching involved in salivary gland morphogenesis IEA
 biological_processGO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis IEA
 biological_processGO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling IEA
 biological_processGO:0061033 secretion by lung epithelial cell involved in lung growth IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005104 fibroblast growth factor receptor binding IEA
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0042056 chemoattractant activity IEA


Pathways (from Reactome)
Pathway description
PI3K Cascade
PIP3 activates AKT signaling
FGFR2b ligand binding and activation
Phospholipase C-mediated cascade; FGFR2
FRS-mediated FGFR1 signaling
PI-3K cascade:FGFR2
SHC-mediated cascade:FGFR2
FRS-mediated FGFR2 signaling
FRS-mediated FGFR3 signaling
FRS-mediated FGFR4 signaling
Negative regulation of FGFR2 signaling
RAF/MAP kinase cascade
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000014505 FGFBP1 / fibroblast growth factor binding protein 1 / O70514* / Q14512*  / complex / reaction






 

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