ENSGALG00000017287


Gallus gallus

Features
Gene ID: ENSGALG00000017287
  
Biological name :FGF6
  
Synonyms : FGF6 / fibroblast growth factor 6
  
Possible biological names infered from orthology : P10767 / P21658
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 73165296
Gene end: 73168929
  
Corresponding Affymetrix probe sets: GgaAffx.11084.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000027889
NCBI entrez gene - 768907     See in Manteia.
RefSeq - XM_001232070
swissprot - F1P5Y5
Ensembl - ENSGALG00000017287
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fgf6aENSDARG00000009351Danio rerio
 fgf6bENSDARG00000045856Danio rerio
 FGF6ENSG00000111241Homo sapiens
 Fgf6ENSMUSG00000000183Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FGF4 / fibroblast growth factor 4 precursor / P08620* / P11403* / fibroblast growth factor 4*ENSGALG0000000756256
FGF20 / fibroblast growth factor 20 / Q9ESL9* / Q9NP95*ENSGALG0000001366331
FGF9 / fibroblast growth factor 9 / P31371* / P54130*ENSGALG0000002574830
FGF10 / fibroblast growth factor 10 / O15520* / O35565*ENSGALG0000001487228
FGF16 / fibroblast growth factor 16 / O43320* / Q9ESL8*ENSGALG0000000780627
FGF12 / fibroblast growth factor 12 / P61328* / P61329*ENSGALG0000003697127
FGF13 / fibroblast growth factor 13 / P70377* / Q92913* / Mus musculus fibroblast growth factor 13 (Fgf13), transcript variant 4, mRNA.*ENSGALG0000000650827
FGF3 / P48801 / Fibroblast growth factor 3 / P11487*ENSGALG0000002685327
FGF7 / fibroblast growth factor 7 / P21781* / P36363*ENSGALG0000002815826
FGF14 / fibroblast growth factor 14 / Q92915*ENSGALG0000001686624
FGF22 / fibroblast growth factor 22 / Q9ESS2* / Q9HCT0*ENSGALG0000004182224
FGF5 / fibroblast growth factor 5 / P12034* / P15656*ENSGALG0000004552119


Protein motifs (from Interpro)
Interpro ID Name
 IPR002209  Fibroblast growth factor family
 IPR008996  Cytokine IL1/FGF
 IPR028242  Fibroblast growth factor 6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001502 cartilage condensation IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0045445 myoblast differentiation IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005104 fibroblast growth factor receptor binding IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
PI3K Cascade
PIP3 activates AKT signaling
FGFR4 ligand binding and activation
FGFR1c ligand binding and activation
FGFR2c ligand binding and activation
Phospholipase C-mediated cascade: FGFR1
Phospholipase C-mediated cascade; FGFR2
Phospholipase C-mediated cascade; FGFR4
Downstream signaling of activated FGFR1
SHC-mediated cascade:FGFR1
PI-3K cascade:FGFR1
FRS-mediated FGFR1 signaling
PI-3K cascade:FGFR2
SHC-mediated cascade:FGFR2
FRS-mediated FGFR2 signaling
FRS-mediated FGFR3 signaling
FRS-mediated FGFR4 signaling
SHC-mediated cascade:FGFR4
PI-3K cascade:FGFR4
Negative regulation of FGFR1 signaling
Negative regulation of FGFR2 signaling
Negative regulation of FGFR4 signaling
RAF/MAP kinase cascade
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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