Manteia

ENSGALG00000014872

Gallus gallus

Features

Gene ID:	ENSGALG00000014872

Biological name :	FGF10

Synonyms :	FGF10 / fibroblast growth factor 10

Possible biological names infered from orthology :	O15520 / O35565

Species:	Gallus gallus

Chr. number:	Z
Strand:	-1
Band:
Gene start:	13974782
Gene end:	14032655

Corresponding Affymetrix probe sets:	Gga.234.1.S1_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000023949 NCBI entrez gene - 395432 See in Manteia. RefSeq - NM_204696 RefSeq - XM_015277235 RefSeq Peptide - NP_990027 swissprot - O42407 Ensembl - ENSGALG00000014872

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
fgf10a	ENSDARG00000030932	Danio rerio
fgf10b	ENSDARG00000100475	Danio rerio
FGF10	ENSG00000070193	Homo sapiens
Fgf10	ENSMUSG00000021732	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
FGF7 / fibroblast growth factor 7 / P21781* / P36363*	ENSGALG00000028158	41
FGF22 / fibroblast growth factor 22 / Q9ESS2* / Q9HCT0*	ENSGALG00000041822	40
FGF3 / P48801 / Fibroblast growth factor 3 / P11487*	ENSGALG00000026853	37
FGF20 / fibroblast growth factor 20 / Q9ESL9* / Q9NP95*	ENSGALG00000013663	32
FGF16 / fibroblast growth factor 16 / O43320* / Q9ESL8*	ENSGALG00000007806	30
FGF9 / fibroblast growth factor 9 / P31371* / P54130*	ENSGALG00000025748	29
FGF4 / fibroblast growth factor 4 precursor / P08620* / P11403* / fibroblast growth factor 4*	ENSGALG00000007562	29
FGF6 / fibroblast growth factor 6 / P10767* / P21658*	ENSGALG00000017287	27
FGF13 / fibroblast growth factor 13 / P70377* / Q92913* / Mus musculus fibroblast growth factor 13 (Fgf13), transcript variant 4, mRNA.*	ENSGALG00000006508	26
FGF12 / fibroblast growth factor 12 / P61328* / P61329*	ENSGALG00000036971	24
FGF5 / fibroblast growth factor 5 / P12034* / P15656*	ENSGALG00000045521	22
FGF14 / fibroblast growth factor 14 / Q92915*	ENSGALG00000016866	21

Protein motifs (from Interpro)

Interpro ID	Name
IPR002209	Fibroblast growth factor family
IPR008996	Cytokine IL1/FGF
IPR028252	Fibroblast growth factor 10

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000132	establishment of mitotic spindle orientation	IEA
biological_process	GO:0000187	activation of MAPK activity	IEA
biological_process	GO:0001656	metanephros development	IEA
biological_process	GO:0001759	organ induction	IEA
biological_process	GO:0001823	mesonephros development	IEA
biological_process	GO:0001974	blood vessel remodeling	IEA
biological_process	GO:0003338	metanephros morphogenesis	IEA
biological_process	GO:0006935	chemotaxis	IEA
biological_process	GO:0007267	cell-cell signaling	IEA
biological_process	GO:0007368	determination of left/right symmetry	IEA
biological_process	GO:0007431	salivary gland development	IEA
biological_process	GO:0007435	salivary gland morphogenesis	IEA
biological_process	GO:0008284	positive regulation of cell proliferation	IEA
biological_process	GO:0008285	negative regulation of cell proliferation	IEA
biological_process	GO:0008543	fibroblast growth factor receptor signaling pathway	IEA
biological_process	GO:0008544	epidermis development	IEA
biological_process	GO:0008589	regulation of smoothened signaling pathway	IEA
biological_process	GO:0009880	embryonic pattern specification	IEA
biological_process	GO:0009887	animal organ morphogenesis	IEA
biological_process	GO:0010468	regulation of gene expression	IEA
biological_process	GO:0010469	regulation of signaling receptor activity	IEA
biological_process	GO:0010631	epithelial cell migration	IEA
biological_process	GO:0010634	positive regulation of epithelial cell migration	IEA
biological_process	GO:0010838	positive regulation of keratinocyte proliferation	IEA
biological_process	GO:0021983	pituitary gland development	IEA
biological_process	GO:0030177	positive regulation of Wnt signaling pathway	IEA
biological_process	GO:0030324	lung development	IEA
biological_process	GO:0030538	embryonic genitalia morphogenesis	IEA
biological_process	GO:0030855	epithelial cell differentiation	IEA
biological_process	GO:0030878	thyroid gland development	IEA
biological_process	GO:0030916	otic vesicle formation	IEA
biological_process	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	IEA
biological_process	GO:0031016	pancreas development	IEA
biological_process	GO:0031069	hair follicle morphogenesis	IEA
biological_process	GO:0031076	embryonic camera-type eye development	IEA
biological_process	GO:0031532	actin cytoskeleton reorganization	IEA
biological_process	GO:0031659	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle	IEA
biological_process	GO:0032781	positive regulation of ATPase activity	IEA
biological_process	GO:0032808	lacrimal gland development	IEA
biological_process	GO:0032925	regulation of activin receptor signaling pathway	IEA
biological_process	GO:0034394	protein localization to cell surface	IEA
biological_process	GO:0035019	somatic stem cell population maintenance	IEA
biological_process	GO:0035108	limb morphogenesis	IEA
biological_process	GO:0035265	organ growth	IEA
biological_process	GO:0042060	wound healing	IEA
biological_process	GO:0042472	inner ear morphogenesis	IEA
biological_process	GO:0042475	odontogenesis of dentin-containing tooth	IEA
biological_process	GO:0042693	muscle cell fate commitment	IEA
biological_process	GO:0043410	positive regulation of MAPK cascade	IEA
biological_process	GO:0043616	keratinocyte proliferation	IEA
biological_process	GO:0045596	negative regulation of cell differentiation	IEA
biological_process	GO:0045739	positive regulation of DNA repair	IEA
biological_process	GO:0045740	positive regulation of DNA replication	IEA
biological_process	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway	IMP
biological_process	GO:0045747	positive regulation of Notch signaling pathway	IEA
biological_process	GO:0045893	positive regulation of transcription, DNA-templated	IEA
biological_process	GO:0045931	positive regulation of mitotic cell cycle	IEA
biological_process	GO:0045944	positive regulation of transcription by RNA polymerase II	IEA
biological_process	GO:0046579	positive regulation of Ras protein signal transduction	IEA
biological_process	GO:0046877	regulation of saliva secretion	IEA
biological_process	GO:0048146	positive regulation of fibroblast proliferation	IEA
biological_process	GO:0048286	lung alveolus development	IEA
biological_process	GO:0048514	blood vessel morphogenesis	IEA
biological_process	GO:0048536	spleen development	IEA
biological_process	GO:0048538	thymus development	IEA
biological_process	GO:0048557	embryonic digestive tract morphogenesis	IEA
biological_process	GO:0048565	digestive tract development	IEA
biological_process	GO:0048566	embryonic digestive tract development	IEA
biological_process	GO:0048645	animal organ formation	IEA
biological_process	GO:0048730	epidermis morphogenesis	IEA
biological_process	GO:0048752	semicircular canal morphogenesis	IEA
biological_process	GO:0048754	branching morphogenesis of an epithelial tube	IEA
biological_process	GO:0048807	female genitalia morphogenesis	IEA
biological_process	GO:0048808	male genitalia morphogenesis	IEA
biological_process	GO:0050671	positive regulation of lymphocyte proliferation	IEA
biological_process	GO:0050673	epithelial cell proliferation	IEA
biological_process	GO:0050674	urothelial cell proliferation	IEA
biological_process	GO:0050677	positive regulation of urothelial cell proliferation	IEA
biological_process	GO:0050678	regulation of epithelial cell proliferation	IEA
biological_process	GO:0050679	positive regulation of epithelial cell proliferation	IEA
biological_process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IEA
biological_process	GO:0050872	white fat cell differentiation	IEA
biological_process	GO:0050918	positive chemotaxis	IEA
biological_process	GO:0050930	induction of positive chemotaxis	IEA
biological_process	GO:0051145	smooth muscle cell differentiation	IEA
biological_process	GO:0051549	positive regulation of keratinocyte migration	IEA
biological_process	GO:0060019	radial glial cell differentiation	IEA
biological_process	GO:0060173	limb development	IEA
biological_process	GO:0060174	limb bud formation	TAS
biological_process	GO:0060425	lung morphogenesis	IEA
biological_process	GO:0060428	lung epithelium development	IEA
biological_process	GO:0060430	lung saccule development	IEA
biological_process	GO:0060436	bronchiole morphogenesis	IEA
biological_process	GO:0060441	epithelial tube branching involved in lung morphogenesis	IEA
biological_process	GO:0060445	branching involved in salivary gland morphogenesis	IEA
biological_process	GO:0060447	bud outgrowth involved in lung branching	IEA
biological_process	GO:0060449	bud elongation involved in lung branching	IEA
biological_process	GO:0060496	mesenchymal-epithelial cell signaling involved in lung development	IEA
biological_process	GO:0060510	type II pneumocyte differentiation	IEA
biological_process	GO:0060513	prostatic bud formation	IEA
biological_process	GO:0060541	respiratory system development	IEA
biological_process	GO:0060594	mammary gland specification	IEA
biological_process	GO:0060595	fibroblast growth factor receptor signaling pathway involved in mammary gland specification	IEA
biological_process	GO:0060615	mammary gland bud formation	IEA
biological_process	GO:0060638	mesenchymal-epithelial cell signaling	NAS
biological_process	GO:0060661	submandibular salivary gland formation	IEA
biological_process	GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis	IEA
biological_process	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	IEA
biological_process	GO:0060667	branch elongation involved in salivary gland morphogenesis	IEA
biological_process	GO:0060879	semicircular canal fusion	IEA
biological_process	GO:0060915	mesenchymal cell differentiation involved in lung development	IEA
biological_process	GO:0061033	secretion by lung epithelial cell involved in lung growth	IEA
biological_process	GO:0061115	lung proximal/distal axis specification	IEA
biological_process	GO:0070075	tear secretion	IEA
biological_process	GO:0070352	positive regulation of white fat cell proliferation	IEA
biological_process	GO:0070371	ERK1 and ERK2 cascade	IEA
biological_process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IEA
biological_process	GO:0070384	Harderian gland development	IEA
biological_process	GO:0071157	negative regulation of cell cycle arrest	IEA
biological_process	GO:0071338	positive regulation of hair follicle cell proliferation	IEA
biological_process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IMP
biological_process	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	IEA
cellular_component	GO:0005576	extracellular region	IEA
cellular_component	GO:0005615	extracellular space	IEA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0009986	cell surface	IEA
cellular_component	GO:0031012	extracellular matrix	IEA
molecular_function	GO:0005104	fibroblast growth factor receptor binding	IEA
molecular_function	GO:0005111	type 2 fibroblast growth factor receptor binding	IEA
molecular_function	GO:0008083	growth factor activity	IEA
molecular_function	GO:0008201	heparin binding	IEA
molecular_function	GO:0042056	chemoattractant activity	IEA

Pathways (from Reactome)

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSGALG00000014505	FGFBP1 / fibroblast growth factor binding protein 1 / O70514* / Q14512*	/ complex / reaction

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr