ENSDARG00000009351


Danio rerio

Features
Gene ID: ENSDARG00000009351
  
Biological name :fgf6a
  
Synonyms : fgf6a / fibroblast growth factor 6a
  
Possible biological names infered from orthology : FGF6 / fibroblast growth factor 6 / P10767 / P21658
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 16945348
Gene end: 16951890
  
Corresponding Affymetrix probe sets: DrAffx.1.76.S1_at (Zebrafish Array)   NM_001001398_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000010978
NCBI entrez gene - 30560     See in Manteia.
RefSeq - NM_001001398
RefSeq Peptide - NP_001001398
swissprot - Q2LGG1
ZFIN ID - ZDB-GENE-980526-559
Ensembl - ENSDARG00000009351
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FGF6ENSGALG00000017287Gallus gallus
 FGF6ENSG00000111241Homo sapiens
 Fgf6ENSMUSG00000000183Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fgf6b / fibroblast growth factor 6b / FGF6* / P21658* / P10767* / fibroblast growth factor 6*ENSDARG0000004585680
fgf4 / fibroblast growth factor 4 / P08620* / P11403*ENSDARG0000010523053
fgf5 / fibroblast growth factor 5 / P12034* / P15656*ENSDARG0000003537731
fgf3 / P48802 / fibroblast growth factor 3 / P11487*ENSDARG0000010154029
fgf22 / fibroblast growth factor 22 / Q9ESS2* / Q9HCT0*ENSDARG0000007651029
fgf9 / fibroblast growth factor 9ENSDARG0000007862529
fgf20a / fibroblast growth factor 20a / FGF20* / Q9NP95* / Q9ESL9* / fibroblast growth factor 20*ENSDARG0000000735629
fgf20b / fibroblast growth factor 20b / FGF20* / Q9NP95* / Q9ESL9* / fibroblast growth factor 20*ENSDARG0000008607028
fgf12a / fibroblast growth factor 12a / FGF12* / P61329* / P61328* / fibroblast growth factor 12*ENSDARG0000002795727
fgf10b / fibroblast growth factor 10b / FGF10* / O15520* / fibroblast growth factor 10*ENSDARG0000010047527
fgf11a / fibroblast growth factor 11a / FGF11* / Q92914* / P70378* / fibroblast growth factor 11*ENSDARG0000006966227
fgf14 / fibroblast growth factor 14 / Q92915*ENSDARG0000004098227
fgf7 / fibroblast growth factor 7 / P21781*ENSDARG0000005938726
fgf13a / fibroblast growth factor 13a / FGF13* / P70377* / Q92913* / fibroblast growth factor 13* / Mus musculus fibroblast growth factor 13 (Fgf13), transcript variant 4, mRNA.*ENSDARG0000003505626
fgf16 / Q2HXK8 / fibroblast growth factor 16 / O43320* / Q9ESL8*ENSDARG0000004223326
fgf11b / fibroblast growth factor 11b / FGF11* / Q92914* / P70378* / fibroblast growth factor 11*ENSDARG0000004390725
fgf10a / fibroblast growth factor 10a / FGF10* / O35565* / O15520* / fibroblast growth factor 10*ENSDARG0000003093225
fgf13b / fibroblast growth factor 13b / FGF13* / P70377* / Q92913* / fibroblast growth factor 13* / Mus musculus fibroblast growth factor 13 (Fgf13), transcript variant 4, mRNA.*ENSDARG0000005663324
fgf12b / fibroblast growth factor 12b / FGF12* / P61328* / fibroblast growth factor 12*ENSDARG0000011352523


Protein motifs (from Interpro)
Interpro ID Name
 IPR002209  Fibroblast growth factor family
 IPR008996  Cytokine IL1/FGF
 IPR028242  Fibroblast growth factor 6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
PI3K Cascade
PIP3 activates AKT signaling
FGFR4 ligand binding and activation
FGFR1c ligand binding and activation
FGFR2c ligand binding and activation
Phospholipase C-mediated cascade: FGFR1
Phospholipase C-mediated cascade; FGFR2
Phospholipase C-mediated cascade; FGFR4
Downstream signaling of activated FGFR1
SHC-mediated cascade:FGFR1
PI-3K cascade:FGFR1
FRS-mediated FGFR1 signaling
PI-3K cascade:FGFR2
SHC-mediated cascade:FGFR2
FRS-mediated FGFR2 signaling
FRS-mediated FGFR3 signaling
FRS-mediated FGFR4 signaling
SHC-mediated cascade:FGFR4
PI-3K cascade:FGFR4
Negative regulation of FGFR1 signaling
Negative regulation of FGFR2 signaling
Negative regulation of FGFR4 signaling
RAF/MAP kinase cascade
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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