ENSGALG00000029282


Gallus gallus

Features
Gene ID: ENSGALG00000029282
  
Biological name :FOXL2
  
Synonyms : forkhead box L2 / FOXL2
  
Possible biological names infered from orthology : Forkhead box protein L2 / O88470 / P58012
  
Species: Gallus gallus
  
Chr. number: 9
Strand: -1
Band:
Gene start: 5720187
Gene end: 5721316
  
Corresponding Affymetrix probe sets: Gga.7539.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045929
NCBI entrez gene - 503512     See in Manteia.
RefSeq - NM_001012612
RefSeq Peptide - NP_001012630
swissprot - Q5J7N5
Ensembl - ENSGALG00000029282
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 foxl2aENSDARG00000042180Danio rerio
 foxl2bENSDARG00000068417Danio rerio
 FOXL2ENSG00000183770Homo sapiens
 Foxl2ENSMUSG00000050397Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOXI1 / forkhead box I1 / Q12951* / Q922I5* / Forkhead box protein I1 *ENSGALG0000000210528
FOXA2 / hepatocyte nuclear factor 3-beta / P35583* / Q9Y261* / forkhead box A2* / Mus musculus forkhead box A2 (Foxa2), transcript variant 3, mRNA.*ENSGALG0000003088927
FOXL1 / forkhead box L1 / Q12952* / Q64731* / Forkhead box protein L1 *ENSGALG0000002927826
FOXI3 / forkhead box I3 / A8MTJ6*ENSGALG0000003745726
FOXB2 / forkhead box B2 / Q5VYV0* / Q64733* / Forkhead box protein B2 *ENSGALG0000002881925
FOXA1 / forkhead box A1 / P35582* / P55317* / Hepatocyte nuclear factor 3-alpha *ENSGALG0000003271325
FOXB1 / forkhead box B1 / Q64732* / Q99853* / Forkhead box protein B1 *ENSGALG0000002749823
FOXS1 / forkhead box S1 / O43638* / Q61574* / Forkhead box protein S1 *ENSGALG0000004301521


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001541 ovarian follicle development IEA
 biological_processGO:0001555 oocyte growth IEA
 biological_processGO:0002074 extraocular skeletal muscle development IEA
 biological_processGO:0006309 apoptotic DNA fragmentation IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007338 single fertilization IEA
 biological_processGO:0008585 female gonad development IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0019101 female somatic sex determination IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0033686 positive regulation of luteinizing hormone secretion IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046881 positive regulation of follicle-stimulating hormone secretion IEA
 biological_processGO:0048048 embryonic eye morphogenesis IEA
 biological_processGO:0060014 granulosa cell differentiation IEA
 biological_processGO:0060065 uterus development IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0045171 intercellular bridge IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding ISS
 molecular_functionGO:0003700 DNA-binding transcription factor activity ISS
 molecular_functionGO:0030331 estrogen receptor binding IEA
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IEA
 molecular_functionGO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
SUMOylation of transcription factors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008435 SUMO1 / Q8QGH2 / Small ubiquitin-related modifier 1 / P63166* / P63165* / small ubiquitin-like modifier 1*  / reaction / complex
 ENSGALG00000006428 UBE2I / P63283 / SUMO-conjugating enzyme UBC9 / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction






 

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