ENSGALG00000031813


Gallus gallus

Features
Gene ID: ENSGALG00000031813
  
Biological name :CASC3
  
Synonyms : cancer susceptibility 3 / CASC3
  
Possible biological names infered from orthology : O15234 / Protein CASC3 / Q8K3W3
  
Species: Gallus gallus
  
Chr. number: 27
Strand: 1
Band:
Gene start: 4793851
Gene end: 4803966
  
Corresponding Affymetrix probe sets: GgaAffx.8602.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047324
Ensembl peptide - ENSGALP00000053962
Ensembl peptide - ENSGALP00000052082
Ensembl peptide - ENSGALP00000050232
NCBI entrez gene - 426135     See in Manteia.
RefSeq - XM_015299555
RefSeq - XM_015299551
RefSeq - XM_015299552
RefSeq - XM_015299553
RefSeq - XM_015299554
RefSeq - XM_015299550
swissprot - A0A1D5PH06
swissprot - A0A1D5PBV0
swissprot - A0A1D5P3R9
swissprot - A0A1D5PM89
Ensembl - ENSGALG00000031813
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 casc3ENSDARG00000029911Danio rerio
 CASC3ENSG00000108349Homo sapiens
 Casc3ENSMUSG00000078676Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR018545  Btz domain
 IPR028544  Protein CASC3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008298 intracellular mRNA localization IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0035145 exon-exon junction complex IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA 3-end processing
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000010689 MAGOH / P50594 / Protein mago nashi homolog / Q96A72* / MAGOHB* / mago homolog B, exon junction complex core component*  / complex
 ENSGALG00000008530 Q5ZM36 / EIF4A3 / Eukaryotic initiation factor 4A-III / Q91VC3* / Gm5580* / Gm8994* / P38919* / eukaryotic translation initiation factor 4A3* / Eukaryotic initiation factor 4A-III Eukaryot...  / complex
 ENSGALG00000009288 RNPS1 / RNA binding protein with serine rich domain 1 / Q15287* / Q99M28*  / complex
 ENSGALG00000033772 UPF2 / UPF2, regulator of nonsense mediated mRNA decay / Q9HAU5* / UPF2 regulator of nonsense transcripts homolog (yeast)*  / complex
 ENSGALG00000016815 UPF3A / UPF3A, regulator of nonsense mediated mRNA decay / Q9H1J1* / UPF3 regulator of nonsense transcripts homolog A (yeast)*  / complex






 

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