ENSGALG00000031928


Gallus gallus

Features
Gene ID: ENSGALG00000031928
  
Biological name :SPTLC2
  
Synonyms : serine palmitoyltransferase long chain base subunit 2 / SPTLC2
  
Possible biological names infered from orthology : O15270 / P97363
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 39307866
Gene end: 39370146
  
Corresponding Affymetrix probe sets: Gga.19466.1.S1_at (Chicken Array)   GgaAffx.12641.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048834
NCBI entrez gene - 423379     See in Manteia.
RefSeq - NM_001006483
RefSeq Peptide - NP_001006483
swissprot - Q5ZJ96
Ensembl - ENSGALG00000031928
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sptlc2aENSDARG00000018976Danio rerio
 sptlc2bENSDARG00000074287Danio rerio
 O15270ENSG00000100596Homo sapiens
 P97363ENSMUSG00000021036Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SPTLC3 / serine palmitoyltransferase long chain base subunit 3 / Q8BG54* / Q9NUV7* / Mus musculus serine palmitoyltransferase, long chain base subunit 3 (Sptlc3), transcript variant 1, mRNA.*ENSGALG0000000903770


Protein motifs (from Interpro)
Interpro ID Name
 IPR001917  Aminotransferase, class-II, pyridoxal-phosphate binding site
 IPR004839  Aminotransferase, class I/classII
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006686 sphingomyelin biosynthetic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009058 biosynthetic process IEA
 biological_processGO:0030148 sphingolipid biosynthetic process IEA
 biological_processGO:0046511 sphinganine biosynthetic process IEA
 biological_processGO:0046512 sphingosine biosynthetic process IEA
 biological_processGO:0046513 ceramide biosynthetic process IEA
 biological_processGO:1904504 positive regulation of lipophagy IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0017059 serine C-palmitoyltransferase complex IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004758 serine C-palmitoyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis
Sphingolipid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000026131 Q8NFR3* / Q925E8* / SPTSSB* / serine palmitoyltransferase small subunit B*  / complex
 ENSGALG00000025755 SPTSSA / serine palmitoyltransferase small subunit A / Gm6993* / Q8R207* / Q969W0*  / complex
 ENSGALG00000027494 SPTSSB / Q8NFR3* / Q925E8* / serine palmitoyltransferase small subunit B*  / complex
 ENSGALG00000013493 SPTLC1 / serine palmitoyltransferase long chain base subunit 1 / O15269* / O35704* / Serine palmitoyltransferase 1 *  / complex






 

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