ENSGALG00000013493


Gallus gallus

Features
Gene ID: ENSGALG00000013493
  
Biological name :SPTLC1
  
Synonyms : serine palmitoyltransferase long chain base subunit 1 / SPTLC1
  
Possible biological names infered from orthology : O15269 / O35704 / Serine palmitoyltransferase 1
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 44651919
Gene end: 44684718
  
Corresponding Affymetrix probe sets: Gga.11928.1.S1_at (Chicken Array)   GgaAffx.24208.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000021940
Ensembl peptide - ENSGALP00000059541
NCBI entrez gene - 426145     See in Manteia.
RefSeq - XM_004949252
swissprot - A0A1L1RLA1
swissprot - E1BQI0
Ensembl - ENSGALG00000013493
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sptlc1ENSDARG00000042995Danio rerio
 O15269ENSG00000090054Homo sapiens
 O35704ENSMUSG00000021468Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004839  Aminotransferase, class I/classII
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006686 sphingomyelin biosynthetic process IEA
 biological_processGO:0009058 biosynthetic process IEA
 biological_processGO:0030148 sphingolipid biosynthetic process IEA
 biological_processGO:0046511 sphinganine biosynthetic process IEA
 biological_processGO:0046512 sphingosine biosynthetic process IEA
 biological_processGO:0046513 ceramide biosynthetic process IEA
 biological_processGO:1904504 positive regulation of lipophagy IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0017059 serine C-palmitoyltransferase complex IEA
 cellular_componentGO:0035339 SPOTS complex IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004758 serine C-palmitoyltransferase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000009037 SPTLC3 / serine palmitoyltransferase long chain base subunit 3 / Q8BG54* / Q9NUV7* / Mus musculus serine palmitoyltransferase, long chain base subunit 3 (Sptlc3), transcript variant 1, mRNA.*  / complex
 ENSGALG00000025755 SPTSSA / serine palmitoyltransferase small subunit A / Gm6993* / Q8R207* / Q969W0*  / complex
 ENSGALG00000026131 Q8NFR3* / Q925E8* / SPTSSB* / serine palmitoyltransferase small subunit B*  / complex
 ENSGALG00000031928 SPTLC2 / serine palmitoyltransferase long chain base subunit 2 / O15270* / P97363*  / complex
 ENSGALG00000027494 SPTSSB / Q8NFR3* / Q925E8* / serine palmitoyltransferase small subunit B*  / complex






 

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