ENSGALG00000034070


Gallus gallus

Features
Gene ID: ENSGALG00000034070
  
Biological name :GAD1
  
Synonyms : GAD1 / glutamate decarboxylase 1
  
Possible biological names infered from orthology : P48318 / Q99259
  
Species: Gallus gallus
  
Chr. number: 7
Strand: -1
Band:
Gene start: 18286593
Gene end: 18311186
  
Corresponding Affymetrix probe sets: Gga.441.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053512
NCBI entrez gene - 395743     See in Manteia.
RefSeq - NM_204913
RefSeq Peptide - NP_990244
swissprot - Q9YI58
Ensembl - ENSGALG00000034070
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gad1aENSDARG00000093411Danio rerio
 gad1bENSDARG00000027419Danio rerio
 GAD1ENSG00000128683Homo sapiens
 Gad1ENSMUSG00000070880Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GAD2 / glutamate decarboxylase 2 / P48320* / Q05329* / glutamic acid decarboxylase 2*ENSGALG0000004043666
GADL1 / glutamate decarboxylase like 1 / Q6ZQY3*ENSGALG0000001144745
HDC / histidine decarboxylase / P19113* / P23738*ENSGALG0000002343619
DDC / dopa decarboxylase / O88533* / P20711* / Aromatic-L-amino-acid decarboxylase *ENSGALG0000001309418


Protein motifs (from Interpro)
Interpro ID Name
 IPR002129  Pyridoxal phosphate-dependent decarboxylase
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase
 IPR021115  Pyridoxal-phosphate binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019752 carboxylic acid metabolic process IEA
 biological_processGO:0035176 social behavior IEA
 biological_processGO:0035641 locomotory exploration behavior IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0043679 axon terminus IEA
 cellular_componentGO:0044306 neuron projection terminus IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0048786 presynaptic active zone IEA
 cellular_componentGO:0060077 inhibitory synapse IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004351 glutamate decarboxylase activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016831 carboxy-lyase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA


Pathways (from Reactome)
Pathway description
GABA synthesis
GABA synthesis, release, reuptake and degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000034070 GAD1 / glutamate decarboxylase 1 / P48318* / Q99259*  / complex
 ENSGALG00000040436 GAD2 / glutamate decarboxylase 2 / P48320* / Q05329* / glutamic acid decarboxylase 2*  / complex






 

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contact: otassy@igbmc.fr