ENSDARG00000027419


Danio rerio

Features
Gene ID: ENSDARG00000027419
  
Biological name :gad1b
  
Synonyms : gad1b / glutamate decarboxylase 1b
  
Possible biological names infered from orthology : GAD1 / glutamate decarboxylase 1 / P48318 / Q99259
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 3827751
Gene end: 3863452
  
Corresponding Affymetrix probe sets: Dr.9917.1.S1_at (Zebrafish Array)   NM_194419_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000144468
Ensembl peptide - ENSDARP00000024162
Ensembl peptide - ENSDARP00000110348
Ensembl peptide - ENSDARP00000157484
NCBI entrez gene - 378441     See in Manteia.
RefSeq - NM_194419
RefSeq Peptide - NP_919400
swissprot - F1Q5U5
swissprot - Q7ZUS3
ZFIN ID - ZDB-GENE-030909-3
Ensembl - ENSDARG00000027419
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GAD1ENSGALG00000034070Gallus gallus
 GAD1ENSG00000128683Homo sapiens
 Gad1ENSMUSG00000070880Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gad1a / glutamate decarboxylase 1a / GAD1* / Q99259* / P48318* / glutamate decarboxylase 1*ENSDARG0000009341183
gad2 / glutamate decarboxylase 2 / P48320* / Q05329* / glutamic acid decarboxylase 2*ENSDARG0000001553760
zgc:163121ENSDARG0000005537056
csad / cysteine sulfinic acid decarboxylase / Q9DBE0* / Q9Y600*ENSDARG0000002634843
hdc / histidine decarboxylase / P19113* / P23738*ENSDARG0000007545417
ddc / dopa decarboxylase / O88533* / P20711* / Aromatic-L-amino-acid decarboxylase *ENSDARG0000001649417


Protein motifs (from Interpro)
Interpro ID Name
 IPR002129  Pyridoxal phosphate-dependent decarboxylase
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase
 IPR021115  Pyridoxal-phosphate binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009449 gamma-aminobutyric acid biosynthetic process IEP
 biological_processGO:0019752 carboxylic acid metabolic process IEA
 biological_processGO:0042136 neurotransmitter biosynthetic process IEP
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016831 carboxy-lyase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA


Pathways (from Reactome)
Pathway description
GABA synthesis
GABA synthesis, release, reuptake and degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000027419 gad1b / glutamate decarboxylase 1b / GAD1* / Q99259* / P48318* / glutamate decarboxylase 1*  / complex
 ENSDARG00000015537 gad2 / glutamate decarboxylase 2 / P48320* / Q05329* / glutamic acid decarboxylase 2*  / complex
 ENSDARG00000093411 gad1a / glutamate decarboxylase 1a / GAD1* / Q99259* / P48318* / glutamate decarboxylase 1*  / complex






 

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