ENSDARG00000015537


Danio rerio

Features
Gene ID: ENSDARG00000015537
  
Biological name :gad2
  
Synonyms : gad2 / glutamate decarboxylase 2
  
Possible biological names infered from orthology : glutamic acid decarboxylase 2 / P48320 / Q05329
  
Species: Danio rerio
  
Chr. number: 24
Strand: -1
Band:
Gene start: 6133147
Gene end: 6158933
  
Corresponding Affymetrix probe sets: Dr.7883.1.A1_at (Zebrafish Array)   DrAffx.2.18.S1_at (Zebrafish Array)   NM_001017708_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000010443
NCBI entrez gene - 550403     See in Manteia.
RefSeq - NM_001017708
RefSeq Peptide - NP_001017708
swissprot - F1R9E8
ZFIN ID - ZDB-GENE-030909-9
Ensembl - ENSDARG00000015537
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GAD2ENSGALG00000040436Gallus gallus
 GAD2ENSG00000136750Homo sapiens
 Gad2ENSMUSG00000026787Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gad1b / glutamate decarboxylase 1b / GAD1* / Q99259* / P48318* / glutamate decarboxylase 1*ENSDARG0000002741963
gad1a / glutamate decarboxylase 1a / GAD1* / Q99259* / P48318* / glutamate decarboxylase 1*ENSDARG0000009341162
zgc:163121ENSDARG0000005537056
csad / cysteine sulfinic acid decarboxylase / Q9DBE0* / Q9Y600*ENSDARG0000002634843
ddc / dopa decarboxylase / O88533* / P20711* / Aromatic-L-amino-acid decarboxylase *ENSDARG0000001649419
hdc / histidine decarboxylase / P19113* / P23738*ENSDARG0000007545417


Protein motifs (from Interpro)
Interpro ID Name
 IPR002129  Pyridoxal phosphate-dependent decarboxylase
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase
 IPR021115  Pyridoxal-phosphate binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009449 gamma-aminobutyric acid biosynthetic process IEP
 biological_processGO:0019752 carboxylic acid metabolic process IEA
 biological_processGO:0042136 neurotransmitter biosynthetic process IEP
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016831 carboxy-lyase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA


Pathways (from Reactome)
Pathway description
GABA synthesis
GABA synthesis, release, reuptake and degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000027419 gad1b / glutamate decarboxylase 1b / GAD1* / Q99259* / P48318* / glutamate decarboxylase 1*  / complex
 ENSDARG00000015537 gad2 / glutamate decarboxylase 2 / P48320* / Q05329* / glutamic acid decarboxylase 2*  / complex
 ENSDARG00000093411 gad1a / glutamate decarboxylase 1a / GAD1* / Q99259* / P48318* / glutamate decarboxylase 1*  / complex






 

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