ENSGALG00000040436


Gallus gallus

Features
Gene ID: ENSGALG00000040436
  
Biological name :GAD2
  
Synonyms : GAD2 / glutamate decarboxylase 2
  
Possible biological names infered from orthology : glutamic acid decarboxylase 2 / P48320 / Q05329
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 16272211
Gene end: 16303104
  
Corresponding Affymetrix probe sets: Gga.13104.1.S1_at (Chicken Array)   Gga.3712.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053644
Ensembl peptide - ENSGALP00000064517
Ensembl peptide - ENSGALP00000055112
Ensembl peptide - ENSGALP00000054933
NCBI entrez gene - 395395     See in Manteia.
RefSeq - XM_015282054
swissprot - A0A1L1S061
swissprot - A0A1D5PQE9
swissprot - A0A1D5PPX6
swissprot - A0A1D5PLC8
Ensembl - ENSGALG00000040436
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gad2ENSDARG00000015537Danio rerio
 GAD2ENSG00000136750Homo sapiens
 Gad2ENSMUSG00000026787Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GAD1 / glutamate decarboxylase 1 / P48318* / Q99259*ENSGALG0000003407048
GADL1 / glutamate decarboxylase like 1 / Q6ZQY3*ENSGALG0000001144731
DDC / dopa decarboxylase / O88533* / P20711* / Aromatic-L-amino-acid decarboxylase *ENSGALG0000001309413
HDC / histidine decarboxylase / P19113* / P23738*ENSGALG0000002343613


Protein motifs (from Interpro)
Interpro ID Name
 IPR002129  Pyridoxal phosphate-dependent decarboxylase
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase
 IPR021115  Pyridoxal-phosphate binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019752 carboxylic acid metabolic process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016831 carboxy-lyase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA


Pathways (from Reactome)
Pathway description
GABA synthesis
GABA synthesis, release, reuptake and degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000034070 GAD1 / glutamate decarboxylase 1 / P48318* / Q99259*  / complex
 ENSGALG00000040436 GAD2 / glutamate decarboxylase 2 / P48320* / Q05329* / glutamic acid decarboxylase 2*  / complex






 

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