ENSMUSG00000070880


Mus musculus

Features
Gene ID: ENSMUSG00000070880
  
Biological name :Gad1
  
Synonyms : Gad1 / glutamate decarboxylase 1 / P48318
  
Possible biological names infered from orthology : Q99259
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: C2
Gene start: 70553072
Gene end: 70602014
  
Corresponding Affymetrix probe sets: 10472707 (MoGene1.0st)   1416561_at (Mouse Genome 430 2.0 Array)   1416562_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117721
Ensembl peptide - ENSMUSP00000117521
Ensembl peptide - ENSMUSP00000119379
Ensembl peptide - ENSMUSP00000119733
Ensembl peptide - ENSMUSP00000092539
Ensembl peptide - ENSMUSP00000116301
NCBI entrez gene - 14415     See in Manteia.
MGI - MGI:95632
RefSeq - XM_017315599
RefSeq - NM_001312900
RefSeq - NM_008077
RefSeq - XM_006498765
RefSeq - XM_006498766
RefSeq - XM_006498767
RefSeq - XM_017315594
RefSeq - XM_017315597
RefSeq Peptide - NP_032103
RefSeq Peptide - NP_001299829
swissprot - Q548L6
swissprot - D3Z5S3
swissprot - P48318
swissprot - D3Z1L8
swissprot - D3Z466
Ensembl - ENSMUSG00000070880
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gad1aENSDARG00000093411Danio rerio
 gad1bENSDARG00000027419Danio rerio
 GAD1ENSGALG00000034070Gallus gallus
 GAD1ENSG00000128683Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gad2 / P48320 / glutamic acid decarboxylase 2 / Q05329* / glutamate decarboxylase 2*ENSMUSG0000002678765
Csad / Q9DBE0 / Cysteine sulfinic acid decarboxylase / Q9Y600*ENSMUSG0000002304443
Gadl1 / glutamate decarboxylase like 1 / Q6ZQY3*ENSMUSG0000005688042
Hdc / P23738 / histidine decarboxylase / P19113*ENSMUSG0000002736019
Ddc / O88533 / Aromatic-L-amino-acid decarboxylase / P20711* / dopa decarboxylase*ENSMUSG0000002018219


Protein motifs (from Interpro)
Interpro ID Name
 IPR002129  Pyridoxal phosphate-dependent decarboxylase
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase
 IPR021115  Pyridoxal-phosphate binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009449 gamma-aminobutyric acid biosynthetic process IEA
 biological_processGO:0019752 carboxylic acid metabolic process IEA
 biological_processGO:0035176 social behavior IMP
 biological_processGO:0035641 locomotory exploration behavior IMP
 biological_processGO:0042136 neurotransmitter biosynthetic process IEA
 biological_processGO:0042493 response to drug IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005938 cell cortex IDA
 cellular_componentGO:0030424 axon IDA
 cellular_componentGO:0043679 axon terminus IDA
 cellular_componentGO:0044306 neuron projection terminus IDA
 cellular_componentGO:0045202 synapse IDA
 cellular_componentGO:0048786 presynaptic active zone IEA
 cellular_componentGO:0060077 inhibitory synapse IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004351 glutamate decarboxylase activity ISO
 molecular_functionGO:0016595 glutamate binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016831 carboxy-lyase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0047485 protein N-terminus binding IEA


Pathways (from Reactome)
Pathway description
GABA synthesis
GABA synthesis, release, reuptake and degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000111 cleft palate "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
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Allelic Composition: Gab1tm1Wbm/Gab1tm1Wbm
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Gad1tm1Tama/Gad1tm1Tama,Gad2tm1Oba/Gad2tm1Oba
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Gad1tm1Oba/Gad1tm1Oba,Gad2tm1Oba/Gad2tm1Oba
Genetic Background: involves: C57BL/6 * CBA

 MP:0000774 reduced brain size "smaller appearance of the brain" [J:35802]
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Allelic Composition: Gad1tm1.1Tama/Gad1+,Pcntm239Asp/Pcntm239Asp
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA * FVB/N

 MP:0000805 abnormal visual cortex morphology "malformation or absence of the area of the occipital cortex concerned with vision" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Maddtm1Ytk/Maddtm1Ytk
Genetic Background: involves: 129X1/SvJ

 MP:0001177 atelectasis "collapse of the lung or any portion of the lung, or decreased or absent air in the lung, resulting in loss of lung volume " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Gab1tm1Wbm/Gab1tm1Wbm
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001270 distended abdomen "abdomen appears curved outward or swollen; can be due to skeletal axial defects, enlarged visceral organs or megacolon" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gab1tm1Wbm/Gab1tm1Wbm
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Gp1bbtm2Frla/Gp1bbtm2Frla
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
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Allelic Composition: Gp1bbtm2Frla/Gp1bbtm2Frla
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0001429 dehydration "excessive water loss from the body or from an organ or bodily part" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:50053]
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Allelic Composition: Gab1tm1Wbm/Gab1tm1Wbm
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001436 abnormal suckling behavior "reduced ability or inability to exert suction by the mouth, or atypical suckling pattern" [J:16461]
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Allelic Composition: Gab1tm1Wbm/Gab1tm1Wbm
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001513 limb grasping "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Drd1tm1(cre)Rpa/Drd1+,Gad1tm1Rpa/Gad1tm1.1Rpa
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

 MP:0001516 abnormal motor coordination/ balance "altered ability of an animal to maintain skillful and effective interaction of movements or maintenance of equilibrium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Drd1tm1(cre)Rpa/Drd1tm1(cre)Rpa
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

 MP:0001575 cyanosis "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159]
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Allelic Composition: Gab1tm1Wbm/Gab1tm1Wbm
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Gad1tm1Oba/Gad1tm1Oba
Genetic Background: involves: C57BL/6 * CBA

 MP:0001953 respiratory failure "cessation of or failure to commence breathing" [MGI:cls, J:60159]
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Allelic Composition: Gad1tm1Tama/Gad1tm1Tama,Gad2tm1Oba/Gad2tm1Oba
Genetic Background: involves: C57BL/6 * CBA

 MP:0001954 respiratory distress "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
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Allelic Composition: Gad1tm1Oba/Gad1tm1Oba
Genetic Background: involves: C57BL/6 * CBA

 MP:0001985 abnormal gustatory system physiology "anomalous perception of taste" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Aspatm1a(EUCOMM)Wtsi/Aspatm1a(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6J * C57BL/6N

 MP:0002081 perinatal lethality "death anytime between E18.5 and postnatal day 1 " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gad1tm1.1Tama/Gad1+,Pcntm239Asp/Pcntm239Asp
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA * FVB/N

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gad1tm1Oba/Gad1+
Genetic Background: involves: C57BL/6 * CBA

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Maddtm1Ytk/Maddtm1Ytk
Genetic Background: involves: 129X1/SvJ

 MP:0002204 abnormal neurotransmitter physiology "aberrant function or production of endogenous signaling molecules secreted by neurons that alter the behavior of neurons or effector cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Gad1tm1Oba/Gad1tm1Oba
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Gad1tm1Oba/Gad1+
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Gad1tm1Oba/Gad1tm1Oba,Gad2tm1Oba/Gad2tm1Oba
Genetic Background: involves: C57BL/6 * CBA

 MP:0002272 abnormal nervous system electrophysiology "anomaly in the function of the nervous system as it relates to electrical phenomena" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Jmjd6tm1.1Gbf/Jmjd6tm1.1Gbf
Genetic Background: C57BL/6-Jmjd6tm1.1Gbf

Allelic Composition: Gad1tm1Tama/Gad1tm1Tama,Gad2tm1Oba/Gad2tm1Oba
Genetic Background: involves: C57BL/6 * CBA

 MP:0002741 small olfactory bulb "reduced size of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [J:79871]
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Allelic Composition: Gad1tm1.1Tama/Gad1+,Pcntm239Asp/Pcntm239Asp
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA * FVB/N

 MP:0002912 abnormal excitatory postsynaptic potential "defect in the potential detected in postsynaptic cells when an excitatory impulse arrives at the synapse causing depolarization" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Glis2tm1Amj/Glis2tm1Amj
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002945 abnormal inhibitory postsynaptic currents "defect in the size or duration of currents detected in postsynaptic cells when an inhibitory impulse arrives at the synapse causing hyperpolarization" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Gp1bbtm2Frla/Gp1bbtm2Frla
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0003052 omphalocele "protrusion of abdominal viscera at the base of the umbilical cord, with a covering membranous sac of peritoneum-amnion" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Gad1tm1Tama/Gad1tm1Tama,Gad2tm1Oba/Gad2tm1Oba
Genetic Background: involves: C57BL/6 * CBA

 MP:0003477 abnormal nerve fiber response "anomaly in the electrophysiological recordings from a single or several nerve fiber(s)" [Nmice:Neuromice Consortium Submission]
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Allelic Composition: Gad1tm1Tama/Gad1tm1Tama,Gad2tm1Oba/Gad2tm1Oba
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Gad1tm1.1Tama/Gad1+,Pkd2l1tm1.1Yuni/Pkd2l1tm1.1Yuni
Genetic Background: involves: 129S/SvEv * C57BL/6 * CBA

 MP:0003492 abnormal involuntary movement "anomalies in movements that occur independent of planning (eg. reflexive behavior)" [Nmice:Neuromice Consortium Submission]
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Allelic Composition: Jmjd6tm1.1Gbf/Jmjd6tm1.1Gbf
Genetic Background: C57BL/6-Jmjd6tm1.1Gbf

 MP:0003632 abnormal nervous system morphology 
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Allelic Composition: Gp1bbtm2Frla/Gp1bbtm2Frla
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gad1tm1.1Tama/Gad1+,Pcntm239Asp/Pcntm239Asp
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA * FVB/N

 MP:0004101 abnormal brain interneuron morphology "malformation or absence of neurons that exclusively interact with other neurons in the brain; this includes most brain neuronal cell types" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Maddtm1Ytk/Maddtm1Ytk
Genetic Background: involves: 129X1/SvJ

Allelic Composition: Gad1tm1Rpa/Gad1+
Genetic Background: Not Specified

Allelic Composition: Gad1tm1.1Rpa/Gad1+
Genetic Background: Not Specified

 MP:0004948 abnormal neuronal precursor proliferation "any anomaly in the ability of a neuroblast population to undergo rapid expansion by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gad1tm1.1Tama/Gad1+,Pcntm239Asp/Pcntm239Asp
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA * FVB/N

 MP:0004994 abnormal brain wave pattern "any anomaly in the standard pattern of rhythmic and rapid fluctuation of electrical potential between parts of the brain, often visualized on an electroencephalogram (EEG); the pattern is often measured to diagnose neurological conditions such as seizure disorders (epilepsy)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Glis2tm1Amj/Glis2tm1Amj
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005039 hypoxia "reduced concentration of O2 in the blood, alveoli or other tissues resulting in the decreased pressure of this component of body gases" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Gab1tm1Wbm/Gab1tm1Wbm
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005584 abnormal enzyme/coenzyme activity "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Gad1tm1Oba/Gad1tm1Oba
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Gad1tm1Oba/Gad1+
Genetic Background: involves: C57BL/6 * CBA

 MP:0006009 abnormal neuronal migration "defective or impaired movement of immature neurons from germinal zones to specific positions where they will reside as they mature" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Gad1tm1Tama/?,Lhx6tm2Vpa/Lhx6tm2Vpa
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * CBA

Allelic Composition: Gad1tm1.1Tama/Gad1+,Pcntm239Asp/Pcntm239Asp
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA * FVB/N

 MP:0006042 increased apoptosis "greater than normal programmed cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Gad1tm1.1Tama/Gad1+,Pcntm239Asp/Pcntm239Asp
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA * FVB/N

 MP:0006254 thin cerebral cortex "decreased depth of the mantle covering the surface of the cerebral hemispheres" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:84683]
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Allelic Composition: Gad1tm1.1Tama/Gad1+,Pcntm239Asp/Pcntm239Asp
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA * FVB/N

 MP:0009247 meteorism "swelling of the abdomen resulting from gas in the intestinal or peritoneal cavity" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Gab1tm1Wbm/Gab1tm1Wbm
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0009546 absent gastric milk in neonates "failure of nursing offspring to ingest milk as indicated by stomach content" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Gad1tm1Oba/Gad1tm1Oba
Genetic Background: involves: C57BL/6 * CBA

 MP:0009743 preaxial polydactyly "duplication of all or part of the first ray on one or more of the autopods" [PMID:19125433]
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Allelic Composition: Gad1tm1.1Tama/Gad1+,Pcntm239Asp/Pcntm239Asp
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA * FVB/N

 MP:0009886 failure of palatal shelf elevation "the palatal shelves fail to move from a vertical position in the orofacial cavity to a horizontal apposition above the developing tongue" [PMID:16680722]
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Allelic Composition: Slc32a1tm1.1Bgc/Slc32a1tm1.1Bgc
Genetic Background: involves: 129X1/SvJ

 MP:0009888 palatal shelves fail to meet at midline "polarized growth towards the midline following palatal shelf elevation does not occur" [PMID:16942766]
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Allelic Composition: Gab1tm1Wbm/Gab1tm1Wbm
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0009890 cleft secondary palate "congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722]
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Allelic Composition: Gab1tm1Wbm/Gab1tm1Wbm
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Gad1tm1.1Bgc/Gad1tm1.1Bgc
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Gad1tm1.1Bgc/Gad1tm1Rpa,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
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Allelic Composition: Drd1tm1(cre)Rpa/Drd1+,Gad1tm1Rpa/Gad1tm1.1Rpa
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

 MP:0010146 umbilical hernia "an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the umbilicus; occurs when the muscle through which blood vessels pass to feed the developing fetus fails to completely close" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", PMID:20333300]
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Allelic Composition: Gad1tm1.1Bgc/Gad1tm1.1Bgc
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Gad1tm1.1Bgc/Gad1tm1Rpa,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL

 MP:0010819 primary atelectasis "nonexpansion of the lungs after birth, seen in stillborn organisms and in live born animals that do not establish respiration" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Gad1tm1Tama/Gad1tm1Tama,Gad2tm1Oba/Gad2tm1Oba
Genetic Background: involves: C57BL/6 * CBA

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Gab1tm1Wbm/Gab1tm1Wbm
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Gad1tm1Oba/Gad1tm1Oba
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Gad1tm1Oba/Gad1tm1Oba,Gad2tm1Oba/Gad2tm1Oba
Genetic Background: involves: C57BL/6 * CBA

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Maddtm1Ytk/Maddtm1Ytk
Genetic Background: involves: 129X1/SvJ

 MP:0011109 partial lethality throughout fetal growth and development "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
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Allelic Composition: Gad1tm1Tama/?,Lhx6tm2Vpa/Lhx6tm2Vpa
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * CBA

Allelic Composition: Gad1tm1Oba/Gad1+,Gad2tm1Oba/Gad2tm1Oba
Genetic Background: involves: C57BL/6 * CBA

 MP:0011400 complete lethality "all individuals of a given genotype in a population die before the end of the normal lifespan but time(s) of death are unspecified" [MGI:llw2]
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Allelic Composition: Nfe2l2tm1Ywk/Nfe2l2tm1Ywk
Genetic Background: B6.129X1-Nfe2l2tm1Ywk/J

 MP:0030248 narrow maxilla "reduced width of the upper bony framework of the mouth where the superior teeth are held" [MGI:anna]
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Allelic Composition: Gab1tm1Wbm/Gab1tm1Wbm
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000026787 Gad2 / P48320 / glutamic acid decarboxylase 2 / Q05329* / glutamate decarboxylase 2*  / complex
 ENSMUSG00000070880 Gad1 / P48318 / glutamate decarboxylase 1 / Q99259*  / complex






 

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