ENSGALG00000035104


Gallus gallus

Features
Gene ID: ENSGALG00000035104
  
Biological name :HAND1
  
Synonyms : HAND1 / heart- and neural crest derivatives-expressed protein 1
  
Possible biological names infered from orthology : heart and neural crest derivatives expressed 1 / O96004 / Q64279
  
Species: Gallus gallus
  
Chr. number: 13
Strand: 1
Band:
Gene start: 12134077
Gene end: 12135178
  
Corresponding Affymetrix probe sets: GgaAffx.21786.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044206
NCBI entrez gene - 395812     See in Manteia.
RefSeq - NM_204965
RefSeq Peptide - NP_990296
swissprot - A0A1D5NV33
Ensembl - ENSGALG00000035104
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HAND1ENSG00000113196Homo sapiens
 Hand1ENSMUSG00000037335Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HAND2 / heart and neural crest derivatives expressed 2 / P61296* / Q61039* / Heart- and neural crest derivatives-expressed protein 2 *ENSGALG0000003053054
TAL1 / T-cell acute lymphocytic leukemia protein 1 homolog / P22091* / P17542* / T cell acute lymphocytic leukemia 1* / TAL bHLH transcription factor 1, erythroid differentiation factor*ENSGALG0000002329620
TCF15 / transcription factor 15 / Q12870* / Q60756*ENSGALG0000002627620
TWIST1 / twist family bHLH transcription factor 1 / P26687* / Q15672* / twist basic helix-loop-helix transcription factor 1*ENSGALG0000004164020
TWIST2ENSGALG0000000427417
TWIST3ENSGALG0000004022017
NHLH1 / helix-loop-helix protein 1 / NHLH2* / Q02575* / Q02576* / Q02577* / Q64221* / nescient helix-loop-helix 2* / nescient helix-loop-helix 1*ENSGALG0000002581716
TAL2 / TAL bHLH transcription factor 2 / Q16559* / Q62282* / T cell acute lymphocytic leukemia 2*ENSGALG0000002311415


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001707 mesoderm formation IEA
 biological_processGO:0001824 blastocyst development IEA
 biological_processGO:0001829 trophectodermal cell differentiation IEA
 biological_processGO:0001947 heart looping IEA
 biological_processGO:0003144 embryonic heart tube formation IEA
 biological_processGO:0003218 cardiac left ventricle formation IEA
 biological_processGO:0003219 cardiac right ventricle formation IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0035050 embryonic heart tube development IEA
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0055010 ventricular cardiac muscle tissue morphogenesis IEA
 biological_processGO:0060411 cardiac septum morphogenesis IEA
 biological_processGO:0060485 mesenchyme development IEA
 biological_processGO:0060536 cartilage morphogenesis IEA
 biological_processGO:0060707 trophoblast giant cell differentiation IEA
 biological_processGO:0061371 determination of heart left/right asymmetry IEA
 biological_processGO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043425 bHLH transcription factor binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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