ENSGALG00000040141


Gallus gallus

Features
Gene ID: ENSGALG00000040141
  
Biological name :H2AFY
  
Synonyms : Core histone macro-H2A.1 / H2AFY / O93327
  
Possible biological names infered from orthology : H2A histone family member Y / O75367 / Q9QZQ8
  
Species: Gallus gallus
  
Chr. number: 13
Strand: 1
Band:
Gene start: 15502505
Gene end: 15547817
  
Corresponding Affymetrix probe sets: Gga.3138.1.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049554
Ensembl peptide - ENSGALP00000063076
Ensembl peptide - ENSGALP00000062606
Ensembl peptide - ENSGALP00000054035
Ensembl peptide - ENSGALP00000049727
Ensembl peptide - ENSGALP00000048704
Ensembl peptide - ENSGALP00000048860
NCBI entrez gene - 395858     See in Manteia.
RefSeq - NM_205007
RefSeq Peptide - NP_990338
swissprot - A0A1D5P9Z6
swissprot - A0A1D5P7L3
swissprot - O93325
swissprot - A0A1L1RUV5
swissprot - O93327
swissprot - A0A1D5PAG4
Ensembl - ENSGALG00000040141
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 h2afyENSDARG00000099329Danio rerio
 H2AFYENSG00000113648Homo sapiens
 H2afyENSMUSG00000015937Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
H2AFY2 / H2A histone family member Y2 / Q8CCK0* / Q9P0M6* / Core histone macro-H2A.2 *ENSGALG0000000479466
H2AFX* / P16104* / P27661* / Histone H2AX * / H2A histone family member X*ENSGALG0000004570523
H2AFJ / histone H2A.J / Q6GSS7* / Q16777* / Q64523* / Q6FI13* / HIST2H2AC* / HIST2H2AA3* / Hist2h2aa1* / HIST2H2AA4* / Hist2h2aa2* / Histone H2A type 2-C * / Histone H2A type 2-A * / histo...ENSGALG0000003834323
P02263 / H2A-VII / Histone H2A-IV / H2AFJ* / Q8R1M2* / Q9BTM1* / Histone H2A.J * / H2A histone family member J*ENSGALG0000002837222
P02263 / H2A-VII / Histone H2A-IV / H2AFJ* / Q8R1M2* / Q9BTM1* / Histone H2A.J * / H2A histone family member J*ENSGALG0000003264522
P02263 / H2A-VII / Histone H2A-IV / H2AFJ* / Q8R1M2* / Q9BTM1* / Histone H2A.J * / H2A histone family member J*ENSGALG0000002994122
P02263 / H2A-VII / Histone H2A-IV / H2AFJ* / Q8R1M2* / Q9BTM1* / Histone H2A.J * / H2A histone family member J*ENSGALG0000002711322
P02263 / H2A-VII / Histone H2A-IV / H2AFJ* / Q8R1M2* / Q9BTM1* / Histone H2A.J * / H2A histone family member J*ENSGALG0000002731522
P02263 / H2A-VII / Histone H2A-IV / H2AFJ* / Q8R1M2* / Q9BTM1* / Histone H2A.J * / H2A histone family member J*ENSGALG0000003157122
P02263 / H2A-VII / Histone H2A-IV / H2AFJ* / Q8R1M2* / Q9BTM1* / Histone H2A.J * / H2A histone family member J*ENSGALG0000003571522
H2AFX* / P16104* / P27661* / Histone H2AX * / H2A histone family member X*ENSGALG0000002644922
ENSGALG0000001677121
ENSGALG0000001677021
H2AFB1* / H2AFB2* / H2AFB3* / P0C5Z0* / P0C5Y9* / H2A histone family member B3* / H2A histone family member B1* / H2A histone family member B2*ENSGALG0000001560911


Protein motifs (from Interpro)
Interpro ID Name
 IPR002119  Histone H2A
 IPR002589  Macro domain
 IPR007125  Histone H2A/H2B/H3
 IPR009072  Histone-fold
 IPR021171  Core histone macro-H2A
 IPR032454  Histone H2A, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006334 nucleosome assembly IEA
 biological_processGO:0006342 chromatin silencing IBA
 biological_processGO:0007549 dosage compensation IEA
 biological_processGO:0019216 regulation of lipid metabolic process IEA
 biological_processGO:0031060 regulation of histone methylation IBA
 biological_processGO:0033128 negative regulation of histone phosphorylation IEA
 biological_processGO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion IEA
 biological_processGO:0040029 regulation of gene expression, epigenetic IEA
 biological_processGO:0045618 positive regulation of keratinocyte differentiation IEA
 biological_processGO:0045814 negative regulation of gene expression, epigenetic IEA
 biological_processGO:0045815 positive regulation of gene expression, epigenetic IEA
 biological_processGO:0051572 negative regulation of histone H3-K4 methylation IEA
 biological_processGO:0061086 negative regulation of histone H3-K27 methylation IEA
 biological_processGO:0071169 establishment of protein localization to chromatin IEA
 biological_processGO:0071901 negative regulation of protein serine/threonine kinase activity IEA
 biological_processGO:1901837 negative regulation of transcription of nucleolar large rRNA by RNA polymerase I IEA
 biological_processGO:1902750 negative regulation of cell cycle G2/M phase transition IEA
 biological_processGO:1902882 regulation of response to oxidative stress IEA
 biological_processGO:1904815 negative regulation of protein localization to chromosome, telomeric region IEA
 cellular_componentGO:0000228 nuclear chromosome IEA
 cellular_componentGO:0000786 nucleosome IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0000793 condensed chromosome IEA
 cellular_componentGO:0001740 Barr body IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005721 pericentric heterochromatin IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0035098 ESC/E(Z) complex IEA
 molecular_functionGO:0000182 rDNA binding IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000979 RNA polymerase II core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001046 core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0010385 double-stranded methylated DNA binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0030291 protein serine/threonine kinase inhibitor activity IEA
 molecular_functionGO:0031490 chromatin DNA binding IEA
 molecular_functionGO:0031492 nucleosomal DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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