ENSGALG00000041900


Gallus gallus

Features
Gene ID: ENSGALG00000041900
  
Biological name :DLG3
  
Synonyms : discs large MAGUK scaffold protein 3 / DLG3
  
Possible biological names infered from orthology : Disks large homolog 3 / P70175 / Q92796
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 2489721
Gene end: 2530898
  
Corresponding Affymetrix probe sets: Gga.5402.1.S1_at (Chicken Array)   GgaAffx.26616.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000054331
NCBI entrez gene - 428706     See in Manteia.
RefSeq - XM_015278413
RefSeq - XM_015278414
RefSeq - XM_015278415
RefSeq - XM_015278416
RefSeq - XM_015278417
RefSeq - XM_015278418
RefSeq - XM_015278419
RefSeq - XM_015278420
RefSeq - XM_426264
RefSeq - XM_015278412
swissprot - A0A1D5PN92
Ensembl - ENSGALG00000041900
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dlg3ENSDARG00000076796Danio rerio
 DLG3ENSG00000082458Homo sapiens
 Dlg3ENSMUSG00000000881Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DLG1 / discs large MAGUK scaffold protein 1 / Q12959* / Q811D0* / Disks large homolog 1 *ENSGALG0000000690866
ENSGALG0000004299232
DLG5 / discs large MAGUK scaffold protein 5 / E9Q9R9* / Q8TDM6* / Disks large homolog 5 *ENSGALG0000004301822
TJP1 / tight junction protein 1 / P39447* / Q07157*ENSGALG0000004255220
MPP5 / membrane palmitoylated protein 5 / Q8N3R9* / Q9JLB2* / membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)*ENSGALG0000000958120
TJP2 / tight junction protein ZO-2 / Q9Z0U1* / Q9UDY2* / AL358113.1* / tight junction protein 2*ENSGALG0000001510919
MPP3 / membrane palmitoylated protein 3 / Q13368*ENSGALG0000004252118
MPP4 / membrane palmitoylated protein 4 / Q6P7F1* / Q96JB8* / MAGUK p55 subfamily member 4 *ENSGALG0000000839818
TJP3 / tight junction protein 3 / O95049*ENSGALG0000000074818
MPP2 / membrane palmitoylated protein 2 / Q14168* / Q9WV34* / Mus musculus membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) (Mpp2), transcript variant 1, mRNA.*ENSGALG0000003558017
MPP6 / membrane palmitoylated protein 6 / Q9JLB0* / Q9NZW5* / membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)*ENSGALG0000001098817
CASK / calcium/calmodulin dependent serine protein kinase / O14936* / O70589* / Peripheral plasma membrane protein CASK *ENSGALG0000004240017
MPP1 / Q5ZJ00 / 55 kDa erythrocyte membrane protein / P70290* / Q00013* / membrane protein, palmitoylated* / membrane palmitoylated protein 1*ENSGALG0000000507115
DLG2* / Q15700* / Q91XM9* / Disks large homolog 2 * / discs large MAGUK scaffold protein 2*ENSGALG0000004122512
MPP7 / membrane palmitoylated protein 7 / Q5T2T1* / MAGUK p55 subfamily member 7 isoform 2 *ENSGALG0000000740811
GUK1 / guanylate kinase 1 / Q16774*ENSGALG000000053368


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001478  PDZ domain
 IPR008144  Guanylate kinase-like domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR016313  Disks large 1-like
 IPR019583  PDZ-associated domain of NMDA receptors
 IPR019590  Disks large homologue 1, N-terminal PEST domain
 IPR020590  Guanylate kinase, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001736 establishment of planar polarity IEA
 biological_processGO:0010923 negative regulation of phosphatase activity IEA
 biological_processGO:0045197 establishment or maintenance of epithelial cell apical/basal polarity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0032281 AMPA glutamate receptor complex IEA
 molecular_functionGO:0019900 kinase binding IEA
 molecular_functionGO:0019902 phosphatase binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA


Pathways (from Reactome)
Pathway description
Activation of Ca-permeable Kainate Receptor
Neurexins and neuroligins
Synaptic adhesion-like molecules


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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