ENSGALG00000042400


Gallus gallus

Features
Gene ID: ENSGALG00000042400
  
Biological name :CASK
  
Synonyms : calcium/calmodulin dependent serine protein kinase / CASK
  
Possible biological names infered from orthology : O14936 / O70589 / Peripheral plasma membrane protein CASK
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 111777485
Gene end: 111982403
  
Corresponding Affymetrix probe sets: Gga.7689.1.S1_at (Chicken Array)   Gga.7689.2.S1_at (Chicken Array)   Gga.7689.2.S1_x_at (Chicken Array)   Gga.7689.3.S1_s_at (Chicken Array)   Gga.9004.1.S1_at (Chicken Array)   GgaAffx.10364.1.S1_s_at (Chicken Array)   GgaAffx.10365.1.S1_at (Chicken Array)   GgaAffx.10365.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048702
Ensembl peptide - ENSGALP00000052215
Ensembl peptide - ENSGALP00000049994
Ensembl peptide - ENSGALP00000045128
NCBI entrez gene - 418565     See in Manteia.
RefSeq - XM_416769
RefSeq - XM_015301649
RefSeq - XM_015301655
RefSeq - XM_015301660
RefSeq - XM_015301588
RefSeq - XM_015301594
RefSeq - XM_015301601
RefSeq - XM_015301606
RefSeq - XM_015301613
RefSeq - XM_015301619
RefSeq - XM_015301624
RefSeq - XM_015301629
RefSeq - XM_015301632
RefSeq - XM_015301645
swissprot - A0A1D5PHD7
swissprot - A0A1D5PB73
swissprot - A0A1D5NXM9
Ensembl - ENSGALG00000042400
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 caskaENSDARG00000059809Danio rerio
 caskbENSDARG00000100119Danio rerio
 CASKENSG00000147044Homo sapiens
 CaskENSMUSG00000031012Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MPP1 / Q5ZJ00 / 55 kDa erythrocyte membrane protein / P70290* / Q00013* / membrane protein, palmitoylated* / membrane palmitoylated protein 1*ENSGALG0000000507128
MPP2 / membrane palmitoylated protein 2 / Q14168* / Q9WV34* / Mus musculus membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) (Mpp2), transcript variant 1, mRNA.*ENSGALG0000003558025
MPP6 / membrane palmitoylated protein 6 / Q9JLB0* / Q9NZW5* / membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)*ENSGALG0000001098824
MPP5 / membrane palmitoylated protein 5 / Q8N3R9* / Q9JLB2* / membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)*ENSGALG0000000958119
MPP3 / membrane palmitoylated protein 3 / Q13368*ENSGALG0000004252118
MPP4 / membrane palmitoylated protein 4 / Q6P7F1* / Q96JB8* / MAGUK p55 subfamily member 4 *ENSGALG0000000839817
DLG1 / discs large MAGUK scaffold protein 1 / Q12959* / Q811D0* / Disks large homolog 1 *ENSGALG0000000690817
DLG3 / discs large MAGUK scaffold protein 3 / P70175* / Q92796* / Disks large homolog 3 *ENSGALG0000004190015
MPP7 / membrane palmitoylated protein 7 / Q5T2T1* / MAGUK p55 subfamily member 7 isoform 2 *ENSGALG0000000740813
DLG5 / discs large MAGUK scaffold protein 5 / E9Q9R9* / Q8TDM6* / Disks large homolog 5 *ENSGALG0000004301813
TJP1 / tight junction protein 1 / P39447* / Q07157*ENSGALG0000004255212
TJP2 / tight junction protein ZO-2 / Q9Z0U1* / Q9UDY2* / AL358113.1* / tight junction protein 2*ENSGALG0000001510911
TJP3 / tight junction protein 3 / O95049*ENSGALG0000000074811
GUK1 / guanylate kinase 1 / Q16774*ENSGALG000000053366
ENSGALG000000429926
DLG2* / Q15700* / Q91XM9* / Disks large homolog 2 * / discs large MAGUK scaffold protein 2*ENSGALG000000412255


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001452  SH3 domain
 IPR001478  PDZ domain
 IPR004172  L27 domain
 IPR008144  Guanylate kinase-like domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR011009  Protein kinase-like domain superfamily
 IPR014775  L27 domain, C-terminal
 IPR020590  Guanylate kinase, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0070509 calcium ion import IEA
 biological_processGO:0090280 positive regulation of calcium ion import IEA
 cellular_componentGO:0005604 basement membrane IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0031982 vesicle IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0042043 neurexin family protein binding IEA


Pathways (from Reactome)
Pathway description
Dopamine Neurotransmitter Release Cycle
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000009107 NRXN1 / D0PRN2 / Neurexin-1-beta / P0DI97* / P58400* / Q9CS84* / Q9ULB1* / neurexin 1*  / complex / reaction
 ENSGALG00000012170 LIN7C / Q5F425 / Protein lin-7 homolog C / C * / Q9NUP9* / O88952* / lin-7 homolog C, crumbs cell polarity complex component*  / complex / reaction
 ENSGALG00000001329 EPB41 / erythrocyte membrane protein band 4.1 / P11171* / P48193*  / reaction / complex






 

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