ENSGALG00000015109


Gallus gallus

Features
Gene ID: ENSGALG00000015109
  
Biological name :TJP2
  
Synonyms : tight junction protein ZO-2 / TJP2
  
Possible biological names infered from orthology : AL358113.1 / Q9UDY2 / Q9Z0U1 / tight junction protein 2
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 34585926
Gene end: 34650856
  
Corresponding Affymetrix probe sets: Gga.448.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049244
Ensembl peptide - ENSGALP00000049603
Ensembl peptide - ENSGALP00000024331
NCBI entrez gene - 395751     See in Manteia.
RefSeq - XM_015280247
RefSeq - XM_015280243
RefSeq - XM_015280244
RefSeq - XM_015280245
RefSeq - XM_015280246
RefSeq - NM_204918
RefSeq - XM_015280242
RefSeq Peptide - NP_990249
swissprot - A0A1D5PA43
swissprot - F1NK34
swissprot - A0A1D5P943
Ensembl - ENSGALG00000015109
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tjp2aENSDARG00000063309Danio rerio
 tjp2bENSDARG00000023443Danio rerio
 AL358113.1ENSG00000285130Homo sapiens
 TJP2ENSG00000119139Homo sapiens
 Tjp2ENSMUSG00000024812Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TJP1 / tight junction protein 1 / P39447* / Q07157*ENSGALG0000004255239
TJP3 / tight junction protein 3 / O95049*ENSGALG0000000074829
DLG5 / discs large MAGUK scaffold protein 5 / E9Q9R9* / Q8TDM6* / Disks large homolog 5 *ENSGALG0000004301815
DLG3 / discs large MAGUK scaffold protein 3 / P70175* / Q92796* / Disks large homolog 3 *ENSGALG0000004190012
DLG1 / discs large MAGUK scaffold protein 1 / Q12959* / Q811D0* / Disks large homolog 1 *ENSGALG0000000690811
MPP3 / membrane palmitoylated protein 3 / Q13368*ENSGALG000000425219
MPP5 / membrane palmitoylated protein 5 / Q8N3R9* / Q9JLB2* / membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)*ENSGALG000000095818
MPP2 / membrane palmitoylated protein 2 / Q14168* / Q9WV34* / Mus musculus membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) (Mpp2), transcript variant 1, mRNA.*ENSGALG000000355808
MPP4 / membrane palmitoylated protein 4 / Q6P7F1* / Q96JB8* / MAGUK p55 subfamily member 4 *ENSGALG000000083988
MPP6 / membrane palmitoylated protein 6 / Q9JLB0* / Q9NZW5* / membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)*ENSGALG000000109887
CASK / calcium/calmodulin dependent serine protein kinase / O14936* / O70589* / Peripheral plasma membrane protein CASK *ENSGALG000000424007
ENSGALG000000429926
MPP1 / Q5ZJ00 / 55 kDa erythrocyte membrane protein / P70290* / Q00013* / membrane protein, palmitoylated* / membrane palmitoylated protein 1*ENSGALG000000050716
MPP7 / membrane palmitoylated protein 7 / Q5T2T1* / MAGUK p55 subfamily member 7 isoform 2 *ENSGALG000000074085
GUK1 / guanylate kinase 1 / Q16774*ENSGALG000000053363
DLG2* / Q15700* / Q91XM9* / Disks large homolog 2 * / discs large MAGUK scaffold protein 2*ENSGALG000000412252


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001478  PDZ domain
 IPR005417  Tight junction protein ZO
 IPR005419  Tight junction protein ZO-2
 IPR008144  Guanylate kinase-like domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0071847 TNFSF11-mediated signaling pathway IEA
 biological_processGO:2001205 negative regulation of osteoclast development IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0070160 occluding junction IEA


Pathways (from Reactome)
Pathway description
Signaling by Hippo
Apoptotic cleavage of cell adhesion proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000010412 WWTR1 / WW domain containing transcription regulator 1 / Q9EPK5* / Q9GZV5*  / complex / reaction
 ENSGALG00000010638 CASP3 / caspase 3 / P42574* / P70677* / Caspase-3 Caspase-3 subunit p17 Caspase-3 subunit p12*  / reaction






 

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