ENSGALG00000043018


Gallus gallus

Features
Gene ID: ENSGALG00000043018
  
Biological name :DLG5
  
Synonyms : discs large MAGUK scaffold protein 5 / DLG5
  
Possible biological names infered from orthology : Disks large homolog 5 / E9Q9R9 / Q8TDM6
  
Species: Gallus gallus
  
Chr. number: 6
Strand: 1
Band:
Gene start: 13203928
Gene end: 13296880
  
Corresponding Affymetrix probe sets: Gga.10734.1.S1_s_at (Chicken Array)   GgaAffx.20805.1.S1_s_at (Chicken Array)   GgaAffx.26375.1.S1_at (Chicken Array)   GgaAffx.3101.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045755
Ensembl peptide - ENSGALP00000055366
Ensembl peptide - ENSGALP00000051562
Ensembl peptide - ENSGALP00000049762
NCBI entrez gene - 423728     See in Manteia.
RefSeq - XM_015288292
RefSeq - XM_421604
swissprot - A0A1D5PR45
swissprot - A0A1D5PFJ5
swissprot - A0A1D5PAJ9
swissprot - A0A1D5NZD7
Ensembl - ENSGALG00000043018
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dlg5aENSDARG00000074059Danio rerio
 dlg5b.1ENSDARG00000090949Danio rerio
 DLG5ENSG00000151208Homo sapiens
 Dlg5ENSMUSG00000021782Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TJP1 / tight junction protein 1 / P39447* / Q07157*ENSGALG0000004255211
TJP3 / tight junction protein 3 / O95049*ENSGALG0000000074810
TJP2 / tight junction protein ZO-2 / Q9Z0U1* / Q9UDY2* / AL358113.1* / tight junction protein 2*ENSGALG0000001510910
DLG1 / discs large MAGUK scaffold protein 1 / Q12959* / Q811D0* / Disks large homolog 1 *ENSGALG0000000690810
DLG3 / discs large MAGUK scaffold protein 3 / P70175* / Q92796* / Disks large homolog 3 *ENSGALG000000419009
MPP3 / membrane palmitoylated protein 3 / Q13368*ENSGALG000000425217
CASK / calcium/calmodulin dependent serine protein kinase / O14936* / O70589* / Peripheral plasma membrane protein CASK *ENSGALG000000424006
MPP4 / membrane palmitoylated protein 4 / Q6P7F1* / Q96JB8* / MAGUK p55 subfamily member 4 *ENSGALG000000083986
MPP5 / membrane palmitoylated protein 5 / Q8N3R9* / Q9JLB2* / membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)*ENSGALG000000095816
MPP7 / membrane palmitoylated protein 7 / Q5T2T1* / MAGUK p55 subfamily member 7 isoform 2 *ENSGALG000000074085
MPP2 / membrane palmitoylated protein 2 / Q14168* / Q9WV34* / Mus musculus membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) (Mpp2), transcript variant 1, mRNA.*ENSGALG000000355805
MPP6 / membrane palmitoylated protein 6 / Q9JLB0* / Q9NZW5* / membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)*ENSGALG000000109885
ENSGALG000000429925
MPP1 / Q5ZJ00 / 55 kDa erythrocyte membrane protein / P70290* / Q00013* / membrane protein, palmitoylated* / membrane palmitoylated protein 1*ENSGALG000000050714
DLG2* / Q15700* / Q91XM9* / Disks large homolog 2 * / discs large MAGUK scaffold protein 2*ENSGALG000000412252
GUK1 / guanylate kinase 1 / Q16774*ENSGALG000000053361


Protein motifs (from Interpro)
Interpro ID Name
 IPR001315  CARD domain
 IPR001452  SH3 domain
 IPR001478  PDZ domain
 IPR006907  Domain of unknown function DUF622
 IPR008144  Guanylate kinase-like domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR011029  Death-like domain superfamily
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001837 epithelial to mesenchymal transition IEA
 biological_processGO:0030011 maintenance of cell polarity IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0030859 polarized epithelial cell differentiation IEA
 biological_processGO:0030901 midbrain development IEA
 biological_processGO:0035331 negative regulation of hippo signaling IEA
 biological_processGO:0035332 positive regulation of hippo signaling IEA
 biological_processGO:0042130 negative regulation of T cell proliferation IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0045176 apical protein localization IEA
 biological_processGO:0045186 zonula adherens assembly IEA
 biological_processGO:0045197 establishment or maintenance of epithelial cell apical/basal polarity IEA
 biological_processGO:0045880 positive regulation of smoothened signaling pathway IEA
 biological_processGO:0051965 positive regulation of synapse assembly IEA
 biological_processGO:0060441 epithelial tube branching involved in lung morphogenesis IEA
 biological_processGO:0060999 positive regulation of dendritic spine development IEA
 biological_processGO:0071896 protein localization to adherens junction IEA
 biological_processGO:0072205 metanephric collecting duct development IEA
 cellular_componentGO:0005913 cell-cell adherens junction IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0036064 ciliary basal body IEA
 molecular_functionGO:0008013 beta-catenin binding IEA
 molecular_functionGO:0008092 cytoskeletal protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr