ENSGALG00000042067


Gallus gallus

Features
Gene ID: ENSGALG00000042067
  
Biological name :SPRY1
  
Synonyms : sprouty RTK signaling antagonist 1 / SPRY1
  
Possible biological names infered from orthology : O43609 / Q9QXV9
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 53714525
Gene end: 53715490
  
Corresponding Affymetrix probe sets: Gga.322.1.S1_at (Chicken Array)   GgaAffx.7512.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051947
NCBI entrez gene - 395583     See in Manteia.
RefSeq - NM_001097524
RefSeq - XM_015276127
RefSeq - XM_015276128
RefSeq Peptide - NP_001090993
swissprot - A4LA71
Ensembl - ENSGALG00000042067
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spry1ENSDARG00000103985Danio rerio
 SPRY1ENSG00000164056Homo sapiens
 Spry1ENSMUSG00000037211Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SPRY2 / protein sprouty homolog 2 / O43597* / Q9QXV8* / sprouty RTK signaling antagonist 2*ENSGALG0000001690654
SPRY3 / sprouty RTK signaling antagonist 3 / O43610*ENSGALG0000000744839
SPRY4 / sprouty RTK signaling antagonist 4 / 4 * / Q9C004* / Q9WTP2*ENSGALG0000003301237


Protein motifs (from Interpro)
Interpro ID Name
 IPR007875  Sprouty
 IPR030783  Protein sprouty homologue 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000132 establishment of mitotic spindle orientation IEA
 biological_processGO:0001656 metanephros development IEA
 biological_processGO:0001657 ureteric bud development IEA
 biological_processGO:0001759 organ induction IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009966 regulation of signal transduction IEA
 biological_processGO:0034260 negative regulation of GTPase activity IEA
 biological_processGO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway IEA
 biological_processGO:0043407 negative regulation of MAP kinase activity IEA
 biological_processGO:0046580 negative regulation of Ras protein signal transduction IEA
 biological_processGO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway IEA
 biological_processGO:0060449 bud elongation involved in lung branching IEA
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA


Pathways (from Reactome)
Pathway description
EGFR downregulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction / complex
 ENSGALG00000038089 EGFR / epidermal growth factor receptor / P00533* / Q01279*  / complex / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction / complex






 

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