ENSGALG00000042148


Gallus gallus

Features
Gene ID: ENSGALG00000042148
  
Biological name :FKBP5
  
Synonyms : FKBP5 / peptidyl-prolyl cis-trans isomerase FKBP5
  
Possible biological names infered from orthology : FK506 binding protein 5 / Q13451 / Q64378
  
Species: Gallus gallus
  
Chr. number: 26
Strand: -1
Band:
Gene start: 67524
Gene end: 84823
  
Corresponding Affymetrix probe sets: Gga.4750.1.S1_s_at (Chicken Array)   GgaAffx.12086.1.S1_at (Chicken Array)   GgaAffx.22637.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049254
NCBI entrez gene - 421186     See in Manteia.
RefSeq - NM_001005431
RefSeq - XM_015298716
RefSeq Peptide - NP_001005431
swissprot - A0A1D5P953
Ensembl - ENSGALG00000042148
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fkbp5ENSDARG00000028396Danio rerio
 FKBP5ENSG00000096060Homo sapiens
 Fkbp5ENSMUSG00000024222Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FKBP4 / peptidyl-prolyl cis-trans isomerase FKBP4 / P30416* / Q02790* / FK506 binding protein 4* / Peptidyl-prolyl cis-trans isomerase FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4, N-te...ENSGALG0000001433157
FKBP1B / FK506 binding protein 1B / P68106* / Q9Z2I2* / Peptidyl-prolyl cis-trans isomerase FKBP1B *ENSGALG0000001650012
FKBP3 / FK506 binding protein 3 / Q00688* / Q62446* / Peptidyl-prolyl cis-trans isomerase FKBP3 *ENSGALG0000001246612
FKBP1C / FKBP1A* / P26883* / P62942* / FK506 binding protein 1C* / FK506 binding protein 1A* / Peptidyl-prolyl cis-trans isomerase FKBP1A *ENSGALG0000002715111


Protein motifs (from Interpro)
Interpro ID Name
 IPR001179  FKBP-type peptidyl-prolyl cis-trans isomerase domain
 IPR001440  Tetratricopeptide repeat 1
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat
 IPR023566  Peptidyl-prolyl cis-trans isomerase, FKBP-type
 IPR031210  Peptidyl-prolyl cis-trans isomerase FKBP5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000413 protein peptidyl-prolyl isomerization IEA
 biological_processGO:0061077 chaperone-mediated protein folding IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 molecular_functionGO:0003755 peptidyl-prolyl cis-trans isomerase activity IEA
 molecular_functionGO:0005528 FK506 binding IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0031072 heat shock protein binding IEA


Pathways (from Reactome)
Pathway description
HSP90 chaperone cycle for steroid hormone receptors (SHR)
ESR-mediated signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000014331 FKBP4 / peptidyl-prolyl cis-trans isomerase FKBP4 / P30416* / Q02790* / FK506 binding protein 4* / Peptidyl-prolyl cis-trans isomerase FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4, N-te...  / reaction
 ENSGALG00000010175 HSP90AB1 / heat shock cognate protein HSP 90-beta / P08238* / P11499* / Heat shock protein HSP 90-beta * / heat shock protein 90 alpha family class B member 1*  / complex / reaction
 ENSGALG00000036837 PTGES3 / prostaglandin E synthase 3 / Q15185* / Q9R0Q7*  / complex / reaction






 

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