ENSGALG00000027151


Gallus gallus

Features
Gene ID: ENSGALG00000027151
  
Biological name :FKBP1C
  
Synonyms : FKBP1C
  
Possible biological names infered from orthology : FK506 binding protein 1A / FK506 binding protein 1C / FKBP1A / P26883 / P62942 / Peptidyl-prolyl cis-trans isomerase FKBP1A
  
Species: Gallus gallus
  
Chr. number: 20
Strand: 1
Band:
Gene start: 10023247
Gene end: 10031218
  
Corresponding Affymetrix probe sets: Gga.4948.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000059012
Ensembl peptide - ENSGALP00000042635
NCBI entrez gene - 374233     See in Manteia.
RefSeq - XM_015296321
RefSeq - NM_204330
RefSeq Peptide - NP_989661
swissprot - Q90ZG0
swissprot - A0A1L1RJT3
Ensembl - ENSGALG00000027151
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FKBP1AENSG00000088832Homo sapiens
 FKBP1CENSG00000198225Homo sapiens
 Fkbp1aENSMUSG00000032966Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FKBP1B / FK506 binding protein 1B / P68106* / Q9Z2I2* / Peptidyl-prolyl cis-trans isomerase FKBP1B *ENSGALG0000001650078
FKBP4 / peptidyl-prolyl cis-trans isomerase FKBP4 / P30416* / Q02790* / FK506 binding protein 4* / Peptidyl-prolyl cis-trans isomerase FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4, N-te...ENSGALG0000001433150
FKBP5 / peptidyl-prolyl cis-trans isomerase FKBP5 / Q13451* / Q64378* / FK506 binding protein 5*ENSGALG0000004214847
FKBP3 / FK506 binding protein 3 / Q00688* / Q62446* / Peptidyl-prolyl cis-trans isomerase FKBP3 *ENSGALG0000001246646


Protein motifs (from Interpro)
Interpro ID Name
 IPR001179  FKBP-type peptidyl-prolyl cis-trans isomerase domain
 IPR023566  Peptidyl-prolyl cis-trans isomerase, FKBP-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000413 protein peptidyl-prolyl isomerization IEA
 biological_processGO:0001889 liver development IEP
 biological_processGO:0001933 negative regulation of protein phosphorylation IEA
 biological_processGO:0003007 heart morphogenesis IEA
 biological_processGO:0006936 muscle contraction ISA
 biological_processGO:0007183 SMAD protein complex assembly ISA
 biological_processGO:0007420 brain development IEP
 biological_processGO:0007507 heart development IEP
 biological_processGO:0009792 embryo development ending in birth or egg hatching IEP
 biological_processGO:0010614 negative regulation of cardiac muscle hypertrophy IMP
 biological_processGO:0010615 positive regulation of cardiac muscle adaptation IMP
 biological_processGO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum IMP
 biological_processGO:0019221 cytokine-mediated signaling pathway ISA
 biological_processGO:0030324 lung development IEP
 biological_processGO:0031000 response to caffeine ISA
 biological_processGO:0031398 positive regulation of protein ubiquitination ISA
 biological_processGO:0032092 positive regulation of protein binding ISA
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity ISA
 biological_processGO:0032880 regulation of protein localization ISA
 biological_processGO:0032925 regulation of activin receptor signaling pathway ISA
 biological_processGO:0042098 T cell proliferation IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling ISA
 biological_processGO:0048536 spleen development IEP
 biological_processGO:0048745 smooth muscle tissue development IEP
 biological_processGO:0050776 regulation of immune response ISA
 biological_processGO:0051209 release of sequestered calcium ion into cytosol IEA
 biological_processGO:0051280 negative regulation of release of sequestered calcium ion into cytosol ISA
 biological_processGO:0055010 ventricular cardiac muscle tissue morphogenesis ISA
 biological_processGO:0055117 regulation of cardiac muscle contraction TAS
 biological_processGO:0060173 limb development IEP
 biological_processGO:0060314 regulation of ryanodine-sensitive calcium-release channel activity IEA
 biological_processGO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity ISA
 biological_processGO:0060347 heart trabecula formation ISA
 biological_processGO:0060452 positive regulation of cardiac muscle contraction IMP
 biological_processGO:0070884 regulation of calcineurin-NFAT signaling cascade IMP
 biological_processGO:0086003 cardiac muscle cell contraction IMP
 biological_processGO:0097435 supramolecular fiber organization ISA
 biological_processGO:1902991 regulation of amyloid precursor protein catabolic process ISA
 biological_processGO:1990000 amyloid fibril formation ISA
 cellular_componentGO:0005623 cell IDA
 cellular_componentGO:0005737 cytoplasm ISA
 cellular_componentGO:0005829 cytosol ISA
 cellular_componentGO:0014802 terminal cisterna IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030018 Z disc ISA
 cellular_componentGO:0030424 axon IDA
 cellular_componentGO:0033017 sarcoplasmic reticulum membrane IEA
 cellular_componentGO:0043204 perikaryon IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0070062 extracellular exosome ISA
 molecular_functionGO:0003755 peptidyl-prolyl cis-trans isomerase activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity ISA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005528 FK506 binding IEA
 molecular_functionGO:0008144 drug binding IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0019855 calcium channel inhibitor activity ISA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0044325 ion channel binding IEA
 molecular_functionGO:0046332 SMAD binding ISA
 molecular_functionGO:0048185 activin binding ISA


Pathways (from Reactome)
Pathway description
TGF-beta receptor signaling activates SMADs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000011442 Q90999 / TGFBR2 / TGF-beta receptor type-2 / Q62312* / P37173* / transforming growth factor beta receptor 2* / transforming growth factor, beta receptor II*  / reaction
 ENSGALG00000033179 TGFBR1 / transforming growth factor beta receptor 1 / P36897* / Q64729* / transforming growth factor, beta receptor I*  / complex / reaction
 ENSGALG00000027151 FKBP1C / FKBP1A* / P26883* / P62942* / FK506 binding protein 1C* / FK506 binding protein 1A* / Peptidyl-prolyl cis-trans isomerase FKBP1A *  / reaction






 

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