ENSGALG00000014331


Gallus gallus

Features
Gene ID: ENSGALG00000014331
  
Biological name :FKBP4
  
Synonyms : FKBP4 / peptidyl-prolyl cis-trans isomerase FKBP4
  
Possible biological names infered from orthology : FK506 binding protein 4 / P30416 / Peptidyl-prolyl cis-trans isomerase FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed / Q02790
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 75721961
Gene end: 75736104
  
Corresponding Affymetrix probe sets: Gga.9013.1.S1_at (Chicken Array)   Gga.9013.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000023115
NCBI entrez gene - 418261     See in Manteia.
RefSeq - NM_001006250
RefSeq Peptide - NP_001006250
swissprot - F1NIM4
Ensembl - ENSGALG00000014331
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fkbp4ENSDARG00000008447Danio rerio
 FKBP4ENSG00000004478Homo sapiens
 Fkbp4ENSMUSG00000030357Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FKBP5 / peptidyl-prolyl cis-trans isomerase FKBP5 / Q13451* / Q64378* / FK506 binding protein 5*ENSGALG0000004214857
FKBP3 / FK506 binding protein 3 / Q00688* / Q62446* / Peptidyl-prolyl cis-trans isomerase FKBP3 *ENSGALG0000001246612
FKBP1C / FKBP1A* / P26883* / P62942* / FK506 binding protein 1C* / FK506 binding protein 1A* / Peptidyl-prolyl cis-trans isomerase FKBP1A *ENSGALG0000002715112
FKBP1B / FK506 binding protein 1B / P68106* / Q9Z2I2* / Peptidyl-prolyl cis-trans isomerase FKBP1B *ENSGALG0000001650011


Protein motifs (from Interpro)
Interpro ID Name
 IPR001179  FKBP-type peptidyl-prolyl cis-trans isomerase domain
 IPR001440  Tetratricopeptide repeat 1
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat
 IPR023566  Peptidyl-prolyl cis-trans isomerase, FKBP-type
 IPR031212  Peptidyl-prolyl cis-trans isomerase FKBP4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000413 protein peptidyl-prolyl isomerization IEA
 biological_processGO:0006463 steroid hormone receptor complex assembly IEA
 biological_processGO:0007566 embryo implantation IEA
 biological_processGO:0030521 androgen receptor signaling pathway IEA
 biological_processGO:0030850 prostate gland development IEA
 biological_processGO:0031503 protein-containing complex localization IEA
 biological_processGO:0046661 male sex differentiation IEA
 biological_processGO:0048608 reproductive structure development IEA
 biological_processGO:0061077 chaperone-mediated protein folding IEA
 cellular_componentGO:0005623 cell IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003755 peptidyl-prolyl cis-trans isomerase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0005528 FK506 binding IDA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0031072 heat shock protein binding IEA
 molecular_functionGO:0035259 glucocorticoid receptor binding IEA
 molecular_functionGO:0051219 phosphoprotein binding IEA


Pathways (from Reactome)
Pathway description
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Attenuation phase
ESR-mediated signaling
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000032992 NR3C1 / glucocorticoid receptor / P04150* / nuclear receptor subfamily 3 group C member 1*  / complex
 ENSGALG00000036837 PTGES3 / prostaglandin E synthase 3 / Q15185* / Q9R0Q7*  / reaction / complex
 ENSGALG00000010175 HSP90AB1 / heat shock cognate protein HSP 90-beta / P08238* / P11499* / Heat shock protein HSP 90-beta * / heat shock protein 90 alpha family class B member 1*  / complex / reaction
 ENSGALG00000042148 FKBP5 / peptidyl-prolyl cis-trans isomerase FKBP5 / Q13451* / Q64378* / FK506 binding protein 5*  / reaction
 ENSGALG00000010035 NR3C2 / mineralocorticoid receptor / P08235* / nuclear receptor subfamily 3 group C member 2*  / complex






 

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