ENSGALG00000036837


Gallus gallus

Features
Gene ID: ENSGALG00000036837
  
Biological name :PTGES3
  
Synonyms : prostaglandin E synthase 3 / PTGES3
  
Possible biological names infered from orthology : Q15185 / Q9R0Q7
  
Species: Gallus gallus
  
Chr. number: 33
Strand: 1
Band:
Gene start: 1622780
Gene end: 1630086
  
Corresponding Affymetrix probe sets: Gga.16496.1.A1_at (Chicken Array)   Gga.4894.1.S1_s_at (Chicken Array)   Gga.4894.1.S1_x_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000058352
NCBI entrez gene - 100859133     See in Manteia.
RefSeq - NM_001276306
RefSeq Peptide - NP_001263235
swissprot - A0A1D5PZE1
Ensembl - ENSGALG00000036837
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptges3aENSDARG00000037284Danio rerio
 ptges3bENSDARG00000089626Danio rerio
 PTGES3ENSG00000110958Homo sapiens
 Ptges3ENSMUSG00000071072Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTGES3L / Gallus gallus prostaglandin E synthase 3 (cytosolic)-like (PTGES3L), mRNA.ENSGALG0000003812938
AARSD1 / Gallus gallus alanyl-tRNA synthetase domain containing 1 (AARSD1), mRNA. / Q3THG9* / Q9BTE6* / alanyl-tRNA synthetase domain containing 1*ENSGALG0000000288010


Protein motifs (from Interpro)
Interpro ID Name
 IPR007052  CS domain
 IPR008978  HSP20-like chaperone


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001516 prostaglandin biosynthetic process IEA
 biological_processGO:0005978 glycogen biosynthetic process IEA
 biological_processGO:0007004 telomere maintenance via telomerase IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0042921 glucocorticoid receptor signaling pathway IEA
 biological_processGO:0043588 skin development IEA
 biological_processGO:0051973 positive regulation of telomerase activity IEA
 biological_processGO:0060430 lung saccule development IEA
 biological_processGO:1905323 telomerase holoenzyme complex assembly IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0070182 DNA polymerase binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
HSP90 chaperone cycle for steroid hormone receptors (SHR)
HSF1 activation
Attenuation phase
Aryl hydrocarbon receptor signalling
ESR-mediated signaling
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000014331 FKBP4 / peptidyl-prolyl cis-trans isomerase FKBP4 / P30416* / Q02790* / FK506 binding protein 4* / Peptidyl-prolyl cis-trans isomerase FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4, N-te...  / complex / reaction
 ENSGALG00000010035 NR3C2 / mineralocorticoid receptor / P08235* / nuclear receptor subfamily 3 group C member 2*  / complex
 ENSGALG00000010175 HSP90AB1 / heat shock cognate protein HSP 90-beta / P08238* / P11499* / Heat shock protein HSP 90-beta * / heat shock protein 90 alpha family class B member 1*  / complex / reaction
 ENSGALG00000009451 PPID / peptidylprolyl isomerase D / Q08752* / Q9CR16* / peptidylprolyl isomerase D (cyclophilin D)*  / complex
 ENSGALG00000036837 PTGES3 / prostaglandin E synthase 3 / Q15185* / Q9R0Q7*  / complex / reaction
 ENSGALG00000010836 AHR / P35869* / AC019117.3* / aryl hydrocarbon receptor* / aryl hydrocarbon receptor isoform 2 *  / complex
 ENSGALG00000032992 NR3C1 / glucocorticoid receptor / P04150* / nuclear receptor subfamily 3 group C member 1*  / complex
 ENSGALG00000040247 AIP / aryl hydrocarbon receptor interacting protein / O00170* / O08915* / AH receptor-interacting protein *  / complex
 ENSGALG00000042148 FKBP5 / peptidyl-prolyl cis-trans isomerase FKBP5 / Q13451* / Q64378* / FK506 binding protein 5*  / reaction / complex






 

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